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Lab Dept:
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Chemistry
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Test Name:
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C5 (FIFTH COMPONENT OF COMPLEMENT)
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General Information
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Lab Order Codes:
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CC5
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Synonyms:
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C5 Complement Component, Serum; Fifth component of complement
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CPT Codes:
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86160 – Complement; antigen, each component
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Test Includes:
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C5 level in mg/dL
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Logistics
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Test Indications:
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Useful for investigating an undetectable total complement (CH50) level and investigating individuals with increased susceptibility to bacterial infection. Diagnosis of C5 deficiency.
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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Mayo Medical Laboratories (Test# 9266)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1- 3 days, test set up Monday - Saturday
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Special Instructions:
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See Patient Preparation
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Specimen
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Specimen Type:
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Blood
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Container:
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Red top tube
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Draw Volume:
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1.5 mL blood
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Processed Volume:
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0.5 mL serum
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Centrifuge specimen, remove serum aliquot and place into a screw-capped, round bottom, plastic vial. Ship and store at frozen temperatures. Forward promptly.
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Patient Preparation:
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Patient must be fasting
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Sample Rejection:
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Specimens other than serum; mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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10.6 – 26.3 mg/dL
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Critical Values:
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N/A
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Limitations:
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The total complement assay should be used as a screen for suspected complement deficiencies before ordering individual complement component assays. A deficiency of an individual component of the complement cascade will result in an undetectable total complement level.
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Methodology:
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Nephelometry
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References:
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Mayo Medical Laboratories Web Page November 2009
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Updates:
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11/12/2009: Reference range update, previously listed as 7.4 - 11.7 mg/dL.
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