Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

C5 (FIFTH COMPONENT OF COMPLEMENT)

General Information

Lab Order Codes:

CC5

Synonyms:

C5 Complement Component, Serum; Fifth component of complement

CPT Codes:

86160 – Complement; antigen, each component

Test Includes:

C5 level in mg/dL

Logistics

Test Indications:

Useful for investigating an undetectable total complement (CH50) level and investigating individuals with increased susceptibility to bacterial infection. Diagnosis of C5 deficiency.

Lab Testing Sections:

Chemistry - Sendouts

Referred to:

Mayo Medical Laboratories (MML Test: 9266/C5AG)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

1- 3 days, test set up Monday - Saturday

Special Instructions:

See Patient Preparation

Specimen

Specimen Type:

Blood

Container:

Red top tube

Draw Volume:

1.5 mL blood

Processed Volume:

0.5 mL serum

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen, remove serum aliquot and place into a screw-capped, round bottom, plastic vial. Ship and store at frozen temperatures. Forward promptly.

Patient Preparation:

Patient must be fasting

Sample Rejection:

Specimens other than serum; mislabeled or unlabeled specimens

Interpretive

Reference Range:

10.6 – 26.3 mg/dL

Critical Values:

N/A

Limitations:

The total complement assay should be used as a screen for suspected complement deficiencies before ordering individual complement component assays. A deficiency of an individual component of the complement cascade will result in an undetectable total complement level.

Methodology:

Nephelometry

References:

Mayo Medical Laboratories Web Page November 2009

Updates:

11/12/2009: Reference range update, previously listed as 7.4 - 11.7 mg/dL.



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