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Lab Dept:
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Chemistry
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Test Name:
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BUPIVACAINE LEVEL
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General Information
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Lab Order Codes:
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BUPI
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Synonyms:
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MarcaineŽ
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CPT Codes:
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80299 – Quantitation of drug, not elsewhere specified
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Test Includes:
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Bupivicaine concentration measured in mcg/mL.
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Logistics
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Test Indications:
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Useful to monitor therapeutic concentration. Assessment of possible CNS or cardiac toxicity associated with use of bupivicaine or levobupivicaine.
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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Mayo Medical Laboratories (MML Test#: 89548)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1 – 8 days, performed Monday
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Special Instructions:
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See Limitations
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Specimen
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Specimen Type:
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Whole blood
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Container:
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Red top tube
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Draw Volume:
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4.5 mL (Minimum: 1.8 mL) blood
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Processed Volume:
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1.5 mL (Minimum: 0.6 mL) serum
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Centrifuge specimen, remove serum aliquot. Store and ship specimen at refrigerated temperatures. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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No established reference values
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Critical Values:
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N/A
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Limitations:
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This assay is to be used for only serum drawn from a vein. Arterial levels are approximately twice venous levels and no clear relationship between arterial levels and toxicity has been established.
This assay measures only total bupivicaine; levels of the free (unbound) portion may correlate more closely with symptoms.
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Methodology:
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Gas Chromatography-Mass Spectrometry (GC-MS)
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References:
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Mayo Medical Laboratories Web Page (May 2009)
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Updates:
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5/18/2009: Mayo moved test from a forward to MedTox to being performed internally at MML. Previously test: 91093
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