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Lab Dept:
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Chemistry
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Test Name:
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METHSUXIMIDE LEVEL
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General Information
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Lab Order Codes:
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CELO (MedTox)
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Synonyms:
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Desmethylmethsuximide, or Celontin®
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CPT Codes:
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83858 - Methsuximide
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Test Includes:
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Methsuximide and Normethsuximide concentrations measured in ug/mL.
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Logistics
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Test Indications:
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Anti-epileptic (anticonvulsant) therapeutic drug monitoring, optimizing dosage and assessing toxicity.
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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MedTox Laboratories (Test#: 78)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1 – 3 days, performed daily
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Special Instructions:
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If this is a STAT order, please check with the provider to see if the specimen should be shipped immediately and performed STAT by the reference lab at an additional cost. If immediate shipment is necessary, please call the lab to make arrangements.
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Specimen
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Specimen Type:
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Blood
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Container:
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Red top tube
Alternate: Green top (Lithium Heparin) tube
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Draw Volume:
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6.0 mL (Minimum: 0.6 mL) blood
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Processed Volume:
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2.0 mL (Minimum: 0.2 mL) serum/plasma
Note: Submission of the minimum volume may result in an elevated reporting limit and inability to repeat analysis.
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Centrifuge specimen, remove serum aliquot into a screw-capped round bottom plastic vial. Store and ship at ambient temperatures. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Specimens other than serum/plasma.
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Interpretive
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Reference Range:
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Desmethylmetsuximide:
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10 - 40 ug/mL
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Critical Values:
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Desmethylmethsuximide: ≥55 ug/mL
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Limitations:
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Reporting limit: 1.0 ug/mL
Submission of the minimum volume may result in an elevated reporting limit and inability to repeat analysis.
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Methodology:
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Gas Liquid Chromatography (GC-FID)
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Contraindications:
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N/A
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References:
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MedTox Laboratories January 2008
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