Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

FELBAMATE LEVEL

General Information

Lab Order Codes:

FELBA

Synonyms:

Felbatol®

CPT Codes:

82542 - Column chromatography/mass spectrometry, analyte not elsewhere specified; quantitative, single stationary and mobile phase

Test Includes:

Felbamate concentration measured in ug/mL.

Logistics

Test Indications:

Determining whether a poor therapeutic response is attributable to noncompliance or lack of drug effectiveness. Monitoring changes in serum concentrations resulting from interactions with co-administered drugs such as barbiturates and phenytoin.

Lab Testing Sections:

Chemistry - Sendouts

Referred to:

MedTox Laboratories (MedTox Test: 165)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

1 – 2 days, test performed daily

Special Instructions:

If this is a STAT order, please check with the provider to see if the specimen should be shipped immediately and performed STAT by the reference lab at an additional cost. If immediate shipment is necessary, please call the lab to make arrangements.

Obtain specimen 1 hour prior to next dose.

Specimen

Specimen Type:

Blood

Container:

Red top tube
Alternate: Green (Lithium Heparin) tube

Draw Volume:

6 mL (Minimum: 0.6 mL) blood

Processed Volume:

2 mL (Minimum: 0.2 mL) serum/plasma

Note: Submission of the minimum volume does not allow for repeat analysis and may result in a QNS (quantity not sufficient) test result.

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen, remove serum aliquot into a screw-capped round bottom plastic vial. Store and ship at refrigerated temperatures. Forward promptly.

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimens

Interpretive

Reference Range:

40 - 100 ug/mL

Note: Stated range of 40 - 100 ug/mL is the observed range of concentrations in patients successfully treated with felbamate without apparent ill effect. The therapeutic range is not established.

Critical Values:

Toxic serum concentrations for felbamate have not been established.

Limitations:

Report Limit: 2 ug/mL

Methodology:

MedTox: Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

References:

MedTox Laboratories (December 2010)

Updates:

6/11/2004: Test moved from MedTox Laboratories to Mayo Medical Laboratories. Note change in reference range from 40 –100 ug/mL to 25 – 100 ug/mL. Change in method from GC-FID to HPLC.
5/6/2010: MedTox CPT update.
7/12/2010: Units update from ug/mL to mcg/mL.
9/27/2010: Method change at Mayo, previously listed as HPLC.
12/6/2010: Information updated for MedTox, Mayo information no longer referenced. All specimens to be sent to MedTox.



  Lab Test Directory
    Chemistry
    Coagulation
    Flow/Immunology
    Hematology
    Microbiology/ Virology
    Other Fluids
    Pathology
    Serology
    Transfusion Services
    Urine/Stool

  Search Lab Test Directory
    List All Documents

  Lab Staff

  E-mail Lab Services