|
|
Lab Dept:
|
Chemistry
|
Test Name:
|
LAMICTAL LEVEL
|
General Information
|
Lab Order Codes:
|
LAMM
|
Synonyms:
|
Lamotrigine
|
CPT Codes:
|
82491- Chromatography, quantitative, column; single analyte not elsewhere specified, single stationary and mobile phase
|
Test Includes:
|
Lamictal level reported in ug/mL.
|
Logistics
|
Test Indications:
|
Monitoring serum concentration of lamictal (lamotrigine), assessing compliance or adjusting lamotrigine dose in patients receiving other anticonvulsant drugs which interact pharmokinetically with lamictal (lamotrigine).
|
Lab Testing Sections:
|
Chemistry - Sendouts
|
Referred to:
|
MedTox Laboratories (Test #:158)
|
Phone Numbers:
Minneapolis:
Saint Paul:
|
|
612-813-6280
|
651-220-6550
|
Test Availability:
|
Daily, 24 hours
|
Turnaround Time:
|
1 – 2 days, test performed daily
|
Special Instructions:
|
If this is a STAT order, please check with the provider to see if the specimen should be shipped immediately and performed STAT by the reference lab at an additional cost. If immediate shipment is necessary, please call the lab to make arrangements.
|
Specimen
|
Specimen Type:
|
Blood
|
Container:
|
Red top tube [Alternate: Green (Lithium Heparin) tube]
|
Draw Volume:
|
6 mL (Minimum: 1 mL) blood
|
Processed Volume:
|
2 mL (Minimum: 0.3 mL) serum
|
Collection:
|
Routine venipuncture
|
Special Processing:
|
Lab Staff: Centrifuge specimen, remove serum aliquot into a screw-capped round bottom plastic vial. Store and ship at refrigerated temperatures. Forward promptly.
|
Patient Preparation:
|
None
|
Sample Rejection:
|
Mislabeled or unlabeled specimens
|
Interpretive
|
Reference Range:
|
2 – 20 ug/mL
Note: Current clinical information suggests the recommended concentrations for lamotrigine during chronic therapy are 2 - 20 ug/mL.
|
Critical Values:
|
N/A
|
Limitations:
|
Reporting Limit: 0.5 ug/mL
|
Methodology:
|
MedTox: Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
|
References:
|
MedTox Laboratories December 2010
|
Updates:
|
6/11/2004: Test moved from MedTox Laboratories to Mayo Medical Laboratories. Note change in reference range from 2.0 – 20.0 ug/mL to 1 – 4 ug/mL.
3/31/2009: Reference range/units change, previously listed as 1-4 ug/mL.
9/27/2010: Method change. Previously listed as HPLC for Mayo.
12/7/2010: Mayo references removed. All testing to be performed at MedTox.
|
