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Lab Dept:
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Chemistry
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Test Name:
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ALPHA-1-ANTITRYPSIN, SERUM
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General Information
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Lab Order Codes:
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AATB
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Synonyms:
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AAT, serum; A1A, serum
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CPT Codes:
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82103 – Alpha-1-antitrypsin; total
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Test Includes:
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Serum alpha-1-antitrypsin concentration in mg/dL
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Logistics
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Test Indications:
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Useful for workup of individuals with suspected disorders such as familial chronic obstructive lung disease.
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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Mayo Medical Laboratories (Test#: 8161)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1 - 2 days, test set up Monday - Saturday
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Special Instructions:
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N/A
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Specimen
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Specimen Type:
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Blood
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Container:
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Red top tube
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Draw Volume:
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3.0 mL (Minimum: 1.5 mL) blood
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Processed Volume:
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1.0 mL (Minimum: 0.5 mL) serum
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Centrifuge specimen, remove serum aliquot into a screw-capped plastic vial. Store and ship at refrigerated temperatures. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Specimens other than serum, mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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100 - 190 mg/dL
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Critical Values:
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N/A
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Limitations:
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Low Alpha-1-antitrypsin (A1A) levels may result from liver disease, and A1A genotyping should be done to confirm A1A deficiency disease.
A1A is an acute phase reactant and any inflammatory process will elevate serum A1A levels.
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Methodology:
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Nephelometry
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References:
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Mayo Medical Laboratories Web Page (February 2010)
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