Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

IBUPROFEN LEVEL

General Information

Lab Order Codes:

IBUP

Synonyms:

AdvilŽ, MotrinŽ, NuprinŽ, RufenŽ

CPT Codes:

82491 - Chromatography, quantitative, column; single analyte not elsewhere specified, single stationary and mobile phase

Test Includes:

Ibuprofen level reported in ug/mL.

Logistics

Test Indications:

Anti-inflammatory, Analgesic therapeutic drug monitoring

Lab Testing Sections:

Chemistry - Sendouts

Referred to:

MedTox Laboratories (MedTox Test: 58)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

1 day

Special Instructions:

Trough levels are most reproducible; serial levels in treatment of cystic fibrosis.

Specimen

Specimen Type:

Blood

Container:

Green top (Li Heparin) or Red top tube

Draw Volume:

3 mL (Minimum: 0.5 mL) blood

Processed Volume:

1 mL (Minimum: 0.1 mL) serum/plasma

Note: Submission of the minimum volume results in an elevated reporting limit and inability to repeat analysis

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen, remove serum/plasma aliquot into a screw-capped round bottom plastic vial. Store and ship at refrigerated temperatures.

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimens

Interpretive

Reference Range:

10.0 – 50.0 ug/mL

Critical Values:

>500 ug/mL

Limitations:

Reporting limit: 1.0 ug/mL

Methodology:

High Performance Liquid Chromatography with Ultraviolet Detection (HPLC-UV)

References:

Medtox Laboratories Web Page (July 2006) www.medtox.com



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