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Lab Dept:
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Chemistry
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Test Name:
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FATTY ACID PROFILE OF LIPIDS
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General Information
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Lab Order Codes:
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FAPR
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Synonyms:
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Fatty Acid Profile, Essential (C12-C22), Serum
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CPT Codes:
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82544 - Column chromatography/mass spectrometry, analyte not elsewhere specified; stable isotope dilution, multiple analytes, quantitative, single stationary and mobile phase
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Test Includes:
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See Reference Range
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Logistics
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Test Indications:
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Useful for evaluating deficiency of essential and other nutritionally beneficial fatty acids. Treatment of essential fatty acid deficiency depends on the cause of the disorder and may include nutritional supplementation of essential fatty acids, linoleic acid (C18:2w6) and alpha-linolenic acid (18:3w3).
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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Mayo Medical Laboratories (Test# FAPM/82426)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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3 – 7 days, test set up Monday - Friday
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Special Instructions:
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See Patient Preparation, include information regarding treatment, family history, and tentative diagnosis.
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Specimen
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Specimen Type:
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Blood
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Container:
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Red top tube
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Draw Volume:
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1.5 mL (Minimum: 0.5 mL) blood.
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Processed Volume:
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0.5 mL (Minimum: 0.15 mL) serum
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Centrifuge specimen and aliquot serum into a plastic screw- capped round bottom vial. Store and ship at frozen temperatures. Forward promptly.
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Patient Preparation:
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Overnight (12-14 hour) fast recommended. Patient must not consume any alcohol for 24 hours before the specimen is drawn.
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Sample Rejection:
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Specimens other than serum or plasma; anticoagulants other than EDTA or heparin; warm specimens; mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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Fatty Acid nmol/mL
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1 - 31 days
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32 days - 1 year
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1 - 17 years
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≥18 years
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Lauric Acid, C12:0
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6 - 190
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6 - 190
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5 - 80
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6 - 90
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Myristic Acid, C14:0
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30 - 320
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30 - 320
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40 - 290
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30 - 450
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Hexadecenoic Acid, C16:1w9
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21 - 69
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21 - 69
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24 - 82
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25 - 105
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Palmitoleic Acid, C16:1w7
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20 - 1020
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20 - 1020
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100 - 670
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110 - 1130
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Palmitic Acid, C16:0
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720 - 3120
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720 - 3120
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960 - 3460
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1480 - 3730
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γ-Linolenic Acid, C18:3w6
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6 - 110
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6 - 110
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9 - 130
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16 - 150
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α-Linolenic Acid, C18:3w3
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10 - 190
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10 - 190
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20 - 120
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50 - 130
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Linolenic Acid, C18:2w6
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350 - 2660
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1000 - 3300
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1600 - 3500
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2270 - 3850
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Oleic Acid, C18:1w9
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250 - 3500
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250 - 3500
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350 - 3500
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650 - 3500
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Vaccenic Acid, C18:1w7
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140 - 720
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140 - 720
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320 - 900
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280 - 740
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Stearic Acid, C18:0
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270 - 1140
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270 - 1140
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280 - 1170
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590 - 1170
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EPA, C20:5w3
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2 - 60
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2 - 60
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8 - 90
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14 - 100
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Arachidonic Acid, C20:4w6
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110 - 1110
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110 - 1110
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350 - 1030
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520 - 1490
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Mead Acid, C20:3w9
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8 - 60
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3 - 24
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7 - 30
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7 - 30
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h-γ-Linolenic Acid, C20:3w6
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30 - 170
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30 - 170
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60 - 220
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50 - 250
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Arachidic Acid, C20:0
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30 - 120
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30 - 120
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30 - 90
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50 - 90
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DHA, C22:6w3
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10 - 220
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10 - 220
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30 - 160
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30 - 250
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DPA, C22:5w6
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3 - 70
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3 - 70
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10 - 50
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10 - 70
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DPA, C22:5w3
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6 - 110
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6 - 110
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30 - 270
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20 - 210
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DTA, C22:4w6
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2 - 50
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2 - 50
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10 - 40
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10 - 80
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Docosenoic Acid, C22:1
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2 - 20
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2 - 20
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4 - 13
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4 - 13
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Nervonic Acid, C24:1w9
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30 - 150
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30 - 150
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50 - 130
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60 - 100
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Triene/Tetraene Ratio
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0.017 - 0.083
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0.013 - 0.050
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0.013 - 0.050
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0.010 - 0.038
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Values Expressed as mmol/L
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Total Saturated Acid
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1.2 - 4.6
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1.2 - 4.6
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1.4 - 4.9
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2.5 - 5.5
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Total Monounsaturated Acid
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0.3 - 4.6
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0.3 - 4.6
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0.5 - 4.4
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1.3 - 5.8
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Total Polyunsaturated Acid
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1.1 - 4.9
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1.1 - 4.9
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1.7 - 5.3
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3.2 - 5.8
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Total w3
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0.0 - 0.4
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0.0 - 0.4
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0.1 - 0.5
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0.2 - 0.5
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Total w6
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0.9 - 4.4
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0.9 - 4.4
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1.6 - 4.7
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3.0 - 5.4
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Total Fatty Acids
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3.3 - 14.0
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3.3 - 14.0
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4.4 - 14.3
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7.3 - 16.8
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Critical Values:
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N/A
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Limitations:
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For nutritional assessment, a 12-14 hour fast is required.
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Methodology:
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Gas chromatography/Mass spectrometry (GC-MS), Stable isotope dilution.
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References:
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Mayo Medical Laboratories Web Page (September 2012)
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Updates:
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12/23/2010: Units update. No change in reference ranges.
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