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Lab Dept:
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Chemistry
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Test Name:
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VITAMIN E
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General Information
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Lab Order Codes:
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VE
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Synonyms:
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Alpha Tocopherol
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CPT Codes:
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84446 – Tocopherol alpha (Vitamin E)
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Test Includes:
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Specific quantitation of alpha-tocopherol reported in mg/L.
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Logistics
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Test Indications:
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Useful for diagnosis of (or evaluation of) individuals with motor and sensory neuropathies, monitoring vitamin E status of premature infants requiring oxygenation, and evaluation of persons with intestinal malabsorption of lipids.
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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Mayo Medical Laboratories (Test# 60297)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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2 – 5 days, test set up Monday – Friday
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Special Instructions:
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See Patient Preparation
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Specimen
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Specimen Type:
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Blood
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Container:
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Red top (plain, no gel) tube
Note: SST (serum separator tube) is not acceptable
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Draw Volume:
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1.5 mL (Minimum: 1 mL) blood
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Processed Volume:
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0.5 mL (Minimum: 0.25 mL) serum
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Collection:
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Protect from light by wrapping in foil. Forward to laboratory promptly.
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Special Processing:
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Lab Staff: Centrifuge specimen immediately, remove serum aliquot into an amber aliquot tube (Mayo Supply T192). Store and ship at refrigerated temperatures. Protect from light at all times. Forward promptly.
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Patient Preparation:
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Patient must be fasting for 12 – 14 hours (overnight fast) and not have ingested alcohol or vitamin supplements for at least 24 hours before specimen is collected. Newborns and premature infants should be drawn just before feeding.
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Sample Rejection:
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SST (serum separator tube) is not acceptable. Warm or lipemic specimens will be rejected. Mislabeled or unlabeled specimens.
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Interpretive
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Reference Range:
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0 - 17 years:
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3.8 - 18.4 mg/L
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≥18 years:
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5.5 – 17.0 mg/L
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Significant deficiency:
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<3.0 mg/L
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Significant excess:
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>40 mg/L
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Critical Values:
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N/A
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Limitations:
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Testing of nonfasting specimens or the use of vitamin supplementation can result in elevated plasma vitamin concentrations. Reference values were established in patients who were fasting.
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Methodology:
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Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS); specific quantitation of alpha-tocopherol.
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References:
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Mayo Medical Laboratories Web Page September 2010
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Updates:
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6/5/2007: Pediatric ranges added.
9/4/2007: Lipemic specimens will be rejected. MML notification due to issues with fat solubility.
9/28/2010: Test code update (now performed only at Mayo New England), specimen volume requirements decreased.
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