Clinics and Departments

Laboratory Services

Lab Dept:


Test Name:


General Information

Lab Order Codes:



Toxicology Screen, blood

CPT Codes:

G0431 – Drug screen, qualitative; multiple drug classes by high complexity test method (e.g., immunoassay, enzyme assay), per patient encounter

Test Includes:

List of drugs screened for in serum/blood: acetaminophen, acetone, acetylmorphine, alprazolam, amitriptyline, amobarbital, amoxapine and metabolite, amphetamine, antidepressants, antipsychotics, barbital, barbiturates, benzodiazepines, benztropine, brompheniramine, bupropion and metabolite, butabarbital, butalbital, caffeine, carbamazepine, carisoprodol, chlordiazepoxide and desmethylchlordiazepoxide, chlorpheniramine, chlorpromazine, chlorzoxazone, clomipramine and desmethylclomipramine, clonazepam, clorazepate (as desmethyldiazepam), clozapine, cocaethyliene, cocaine and metabolite, codeine, cyclobenzaprine, desalkylflurazepam, desipramine, desmethyldiazepam, dextromethorphan (as methorphan), diazepam, diltazem, diphenhydramine, doxepin and desmethyldoxepin, doxylamine, ephedrine (and/or pseudoephendrine), ethosuximide, ethyl alcohol, fluoxetine and norfluoxetine, flurazepam and metabolite, fluvoxamine, glutethimide, guaifenesin, halazepam, heroin (as acetylmorphine and morphine), hydrocodone, hydromorphone, hydroxyzine, ibuprofen, imipramine, isopropyl alcohol, ketoprofen, lidocaine, lorazepam, loxapine and metabolite, maprotiline, marijuana and metabolite, mefenamic acid, meperidine and normeperidine, mephobarbital, mepivacaine, meprobamate, mesoridazine, methadone, methamphetamine, methapyrilene, methaqualone, methocarbamol, methorphan, methyl alcohol, methylphenidate, metopolol, midazolam, morphine, naproxen, nifedipine, nortriptyline, opiates, orphenadrine, oxaprozin, oxazepam, oxycodone, paroxetine, pentazocine, pentobarbital, perphenazine, phenacetin, phencyclidine, phenmetrazine, phenobarbital, phentermine, phenylpropanolamine, phenytoin, prazepam (as desmethyldiazepam), primidone, procainamide, procaine, prochlorperazine, promazine, promethazine, propoxyphene and metabolite, propranolol, protriptyline, pseudoephedrine (and/or ephedrine), pyrilamine, quazepam (as desalkylflurazepam), salicylate, secobarbital, sertraline and desmethylsertraline, temazepam, THC (marijuana) and metabolite, theophylline, thiopental, thiordazine, tolmetin, tramadol and metabolite, trazodone, triazolam, trihexyphenidiyl, trimipramine, tripelennamine, valproic acid, velafazine and metabolite, and verapamil. This list is not necessarily inclusive of all possible drugs that could be identified.


Test Indications:


Lab Testing Sections:

Chemistry - Sendouts

Referred to:

MedTox Laboratories (MedTox Test# 21307)

Phone Numbers:

Mpls Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

Routine: 5 days, Stat: 1 day

Special Instructions:



Specimen Type:



Red top tube or Green top (Li Heparin)

Draw Volume:

9 mL (Minimum: 9 mL) blood

Processed Volume:

3 mL (Minimum 3 mL) serum or plasma

Note: Submission of <3 mL of serum or plasma could result in certain drug levels being reported as QNS as well as the inability to retest any questionable results.


Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen, remove serum aliquot into a screw-capped round bottom plastic vial. Ship and store specimen at refrigerated temperatures. Forward promptly.

Patient Preparation:


Sample Rejection:

Mislabeled or unlabeled specimens


Reference Range:


Critical Values:

Positive values




Immunoassay (IA); Gas Chromatography/Flame Ionization Detection (GC-FID); Gas Chromatography/Mass Spectrometry (GC/MS); Confirmation: Various


MedTox Laboratories Web Page April 2013


5/3/2010: CPT update.
2/8/2011: CPT update.
1/7/2012: Test # from 305 to 21307, updated list of drugs screened.
4/6/2013: Draw volume increase due to QNS reporting.
1/12/2015: CPT update
5/18/2015: CPT update
8/20/2015 CPT update G0434 removed

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