Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

VITAMIN K1

General Information

Lab Order Codes:

VK

Synonyms:

Vitamin K; Phylloquinone

CPT Codes:

84597 – Vitamin K

Test Includes:

Vitamin K1 level reported in ng/mL.

Logistics

Test Indications:

Monitor Vitamin K1 levels, assessment of circulating Vitamin K1 concentration.

Lab Testing Sections:

Chemistry - Sendouts

Referred to:

Mayo Medical Laboratories (Mayo Test# VIK1)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

2 - 4 days, test performed Monday - Friday

Special Instructions:

See Patient Preparation

Specimen

Specimen Type:

Blood

Container:

Red top tube

Draw Volume:

6 mL (Minimum: 2.2 mL) blood

Processed Volume:

2 mL (Minimum: 0.75 mL) serum

Collection:

Routine venipuncture. Protect from light. Avoid hemolysis. Forward specimen to laboratory promptly.

Special Processing:

Lab Staff: Centrifuge specimen immediately. Remove serum aliquot into a Mayo Supply T192 amber vial. Store and ship at refrigerated temperatures. Forward promptly. Specimen needs to be protected from the light at all times.

Patient Preparation:

Fasting sample recommended (12 – 14 hour fast), infants should be drawn prior to next feeding.

Patient should not consume alcohol for 1 day prior to blood draw or consume supplements containing Vitamin K.

Sample Rejection:

Gross hemolysis; mild or gross lipemia; mislabeled or unlabeled specimens

Interpretive

Reference Range:

<18 years:

Not established

> or = 18 years:

0.10 – 2.20 ng/mL

Interpretation: Low vitamin K1 concentrations in the serum are indicative of insufficiency and poor vitamin K1 status.

Critical Values:

N/A

Limitations:

Testing of non-fasting specimens or the use of vitamin K1 supplementation can result in elevated serum vitamin K1 concentrations.

Methodology:

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

References:

Mayo Medical Laboratories Web Page April 2013

Updates:

4/3/2013: Testing moved from ARUP to internal at MML. Method previously listed as HPLC.



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