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Lab Dept:
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Chemistry
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Test Name:
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VITAMIN K1
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General Information
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Lab Order Codes:
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VK
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Synonyms:
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Vitamin K; Phylloquinone
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CPT Codes:
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84597 – Vitamin K
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Test Includes:
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Vitamin K1 level reported in ng/mL.
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Logistics
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Test Indications:
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Monitor Vitamin K1 levels, assessment of circulating Vitamin K1 concentration.
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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Mayo Medical Laboratories (Mayo Test# VIK1)
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Phone Numbers:
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MIN Lab: 612-813-6280
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STP Lab: 651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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2 - 4 days, test performed Monday - Friday
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Special Instructions:
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See Patient Preparation
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Specimen
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Specimen Type:
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Blood
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Container:
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Red top tube
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Draw Volume:
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6 mL (Minimum: 2.2 mL) blood
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Processed Volume:
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2 mL (Minimum: 0.75 mL) serum
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Collection:
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Routine venipuncture. Protect from light. Avoid hemolysis. Forward specimen to laboratory promptly.
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Special Processing:
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Lab Staff: Centrifuge specimen immediately. Remove serum aliquot into a Mayo Supply T192 amber vial. Store and ship at refrigerated temperatures. Forward promptly. Specimen needs to be protected from the light at all times.
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Patient Preparation:
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Fasting sample recommended (12 – 14 hour fast), infants should be drawn prior to next feeding.
Patient should not consume alcohol for 1 day prior to blood draw or consume supplements containing Vitamin K.
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Sample Rejection:
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Gross hemolysis; mild or gross lipemia; mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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<18 years:
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Not established
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> or = 18 years:
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0.10 – 2.20 ng/mL
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Interpretation: Low vitamin K1 concentrations in the serum are indicative of insufficiency and poor vitamin K1 status.
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Critical Values:
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N/A
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Limitations:
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Testing of non-fasting specimens or the use of vitamin K1 supplementation can result in elevated serum vitamin K1 concentrations.
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Methodology:
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Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
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References:
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Mayo Medical Laboratories Web Page April 2013
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Updates:
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4/3/2013: Testing moved from ARUP to internal at MML. Method previously listed as HPLC.
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