Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

LORAZEPAM LEVEL

General Information

Lab Order Codes:

LORA

Synonyms:

AtivanŽ

CPT Codes:

80154 – Benzodiazepines

Test Includes:

Lorazepam level reported in ng/mL.

Logistics

Test Indications:

Monitor therapeutic anticonvulsant, sedative

Lab Testing Sections:

Chemistry - Sendouts

Referred to:

MedTox Laboratories (MedTox Test: 64)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

1 – 5 days

Special Instructions:

Trough levels are most reproducible.

Specimen

Specimen Type:

Blood

Container:

Green top (Li Heparin) or Red top tube

Draw Volume:

6 mL (Minimum: 1 mL) blood

Processed Volume:

2 mL (Minimum 0.3 mL) serum/plasma

Note: Submission of the minimum volume results in an elevated reporting range and inability to repeat analysis.

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen, remove serum/plasma aliquot into a screw-capped round bottom plastic vial. Store and ship at refrigerated temperatures. Forward promptly.

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimens

Interpretive

Reference Range:

50.0 – 240.0 ng/mL

Critical Values:

>500.0 ng/mL

Limitations:

Reporting limit: <10.0 ng/mL

Methodology:

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

References:

MedTox Laboratories Web Page (November 2012)

Updates:

CPT Update: Previuosly reported as 80154 – Benzodiazepines.
11/5/2012: Method update, previously listed Gas Chromatography/Electron Capture Detection (GC-EC).



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