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Lab Dept:
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Chemistry
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Test Name:
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PENTOBARBITAL
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General Information
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Lab Order Codes:
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PENT
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Synonyms:
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Nembutal®, Sodium Pentobarbital
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CPT Codes:
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82491 – Chromatography, quantitative, column; single analyte not elsewhere specified, single stationary and mobile phase
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Test Includes:
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Pentobarb level reported in ug/mL.
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Logistics
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Test Indications:
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Therapeutic sedative/hypnotic monitoring
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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MedTox Laboratories (Test# 90)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1-3 days
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Special Instructions:
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Trough levels are most reproducible.
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Specimen
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Specimen Type:
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Blood
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Container:
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Green top (Li Heparin) or Red top tube
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Draw Volume:
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6 mL (Minimum: 1 mL) blood
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Processed Volume:
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2 mL (Minimum 0.3 mL) serum/plasma
Note: Submission of the minimum volume results in an elevated reporting range and inability to repeat analysis.
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Centrifuge specimen, remove serum/plasma aliquot into a screw-capped round bottom plastic vial. Store and ship at refrigerated temperatures. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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1.0 – 5.0 ug/mL
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Critical Values:
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>50.0 ug/mL
Note: Pentobarbital concentrations as high as 50 ug/ml may be required to induce therapeutic coma.
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Limitations:
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<0.3 ug/mL reporting limit
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Methodology:
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Gas Chromatography/Nitrogen Phosphorus Detection (GC-NPD)
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References:
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MedTox Laboratories (May 2010)
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Updates:
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5/6/2010: CPT Update, previously reported as 82205 – Barbituates, not elsewhere specified
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