Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

TOPIRAMATE LEVEL

General Information

Lab Order Codes:

TOPX

Synonyms:

Topomax®; Topiragen

CPT Codes:

80201 - Topiramate

Test Includes:

Topiramate concentration measured in ug/mL.

Logistics

Test Indications:

Measurement of topiramate serum concentration is useful for monitoring dosage compliance and to guide dose adjustment during co-therapy with phenytoin or carbamazepine.

Lab Testing Sections:

Chemistry

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

8 hours

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Red top tube [Alternate: Green (Lithium Heparin) tube]

Draw Volume:

3 mL (Minimum 0.6 mL) blood

Processed Volume:

1 mL (Minimum: 0.2 mL) serum/plasma

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen, remove serum aliquot into a screw-capped round bottom plastic vial. Store and ship at refrigerated temperatures. Forward promptly.

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimens

Interpretive

Reference Range:

2.0 – 25.0 ug/mL

Critical Values:

N/A

Limitations:

Reporting limit 1.5 ug/mL

Methodology:

Immunoassay (IA)

References:

ARK Diagnostics, Inc (Revised August 2012) Package insert for the ARK Topiramate Assay, ARK Diagnostics, Inc, 48089 Fremont Blvd, Fremont, CA 94538, USA, 1600-0105-00, Rev 04, Printed in the USA

ARK™ Antiepileptic therapeutic Drug Monitoring Assays (February 2012) for Siemens Dimension RXL System, UDP 11-018 Rev 02 Siemens RXL, ARK Diagnostics, Inc

Epilepsia (Sunday, December 3, 2006) Poster Session II 7:30 am – 4:30 pm. Article first published online: 30 Oct 2006

http://www.nlm.nih.gov/medlineplus/druginfo/meds/a697012.html

Torrent Pharma Inc., (Revised August 2011) 5380 Holiday Terrace, Suite 40, Kalamazoo, Michigan 49009, 8029987

Updates:

6/11/2004: Test moved from MedTox Laboratories to Mayo Medical Laboratories. Note change in reference range from 2.0 – 25.0 ug/mL to peak and trough specific ranges listed under Reference Range: above. Method has changed from Immunoassay to Fluorescence Polarization Immunoassay (FPIA).
1/30/2008: MML Transport temperature changed from refrigerated to frozen.
12/7/2010: Information updated for MedTox, Mayo information no longer referenced. All specimens to be sent to MedTox.
11/15/2013: Moved from MedTox to internal test at Children’s laboratory.



  Lab Test Directory
    Chemistry
    Coagulation
    Flow/Immunology
    Hematology
    Microbiology/ Virology
    Other Fluids
    Pathology
    Serology
    Transfusion Services
    Urine/Stool

  Search Lab Test Directory
    List All Documents

  Lab Staff

  E-mail Lab Services