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Lab Dept:
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Chemistry
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Test Name:
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TOPIRAMATE LEVEL
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General Information
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Lab Order Codes:
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TOPI
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Synonyms:
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Topomax®
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CPT Codes:
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80201 - Topiramate
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Test Includes:
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Topiramate concentration measured in ug/mL.
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Logistics
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Test Indications:
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Measurement of topiramate serum concentration is useful for monitoring dosage compliance and to guide dose adjustment during co-therapy with phenytoin or carbamazepine.
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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MedTox Laboratories (Test#: 280)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1 day
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Special Instructions:
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If dosage and dosing information are provided, they will be included on the report.
If this is a STAT order, please check with the provider to see if the specimen should be shipped immediately and performed STAT by the reference lab at an additional cost. If immediate shipment is necessary, please call the lab to make arrangements.
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Specimen
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Specimen Type:
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Blood
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Container:
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Red top tube [Alternate: Green (Lithium Heparin) tube]
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Draw Volume:
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3 mL (Minimum 0.6 mL) blood
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Processed Volume:
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1 mL (Minimum: 0.2 mL) serum/plasma
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Centrifuge specimen, remove serum aliquot into a screw-capped round bottom plastic vial. Store and ship at refrigerated temperatures. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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2.0 – 25.0 ug/mL
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Critical Values:
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N/A
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Limitations:
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Reporting limit 0.5 ug/mL
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Methodology:
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Immunoassay (IA)
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References:
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MedTox Laboratories December 2010
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Updates:
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6/11/2004: Test moved from MedTox Laboratories to Mayo Medical Laboratories. Note change in reference range from 2.0 – 25.0 ug/mL to peak and trough specific ranges listed under Reference Range: above. Method has changed from Immunoassay to Fluorescence Polarization Immunoassay (FPIA).
1/30/2008: MML Transport temperature changed from refrigerated to frozen.
12/7/2010: Information updated for MedTox, Mayo information no longer referenced. All specimens to be sent to MedTox.
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