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Lab Dept:
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Chemistry
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Test Name:
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CYANIDE LEVEL
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General Information
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Lab Order Codes:
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CYAN
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Synonyms:
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Amygdalin; Laetrile
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CPT Codes:
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82600 - Cyanide
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Test Includes:
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Cyanide level reported in mcg/mL.
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Logistics
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Test Indications:
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Useful for monitoring possible exposure to cyanide, establishing the cause of death in cyanide exposure.
This test is not useful in monitoring nitroprusside therapy. The preferred test for this would be Thiocyanate.
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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Mayo Medical Laboratories (Test# 8691)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1 – 4 days, test set up Sunday – Friday
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Special Instructions:
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N/A
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Specimen
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Specimen Type:
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Whole blood
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Container:
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Lavender top (EDTA) tube
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Draw Volume:
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3 mL (Minimum: 1.5 mL) blood
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Processed Volume:
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Same as Draw Volume
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Do Not centrifuge. Send as whole blood in original collection container. Store and ship at ambient temperatures. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Specimens other than whole blood; mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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Normal: <0.2 mcg/mL
This test was developed and its performance characteristics determined by Laboratory Medicine and Pathology, Mayo Clinic. This test has not been cleared or approved by the US Food and Drug Administration.
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Critical Values:
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Toxic concentration: ≥2.0 mcg/mL
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Limitations:
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Concentrations as high as 8.0 mcg/mL without symptoms of cyanide toxicity are commonly associated with nitroprusside therapy; one should monitor thiocyanate to determine the potential for intoxication during nitroprusside therapy for hypertensive crisis.
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Methodology:
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Colorimetric
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References:
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Mayo Medical Laboratories (July 2010)
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Updates:
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7/12/2010: Units update from ug/mL to mcg/mL.
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