Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

CYANIDE LEVEL

General Information

Lab Order Codes:

CYAN

Synonyms:

Amygdalin; Laetrile

CPT Codes:

82600 - Cyanide

Test Includes:

Cyanide level reported in mcg/mL.

Logistics

Test Indications:

Useful for monitoring possible exposure to cyanide, establishing the cause of death in cyanide exposure.

This test is not useful in monitoring nitroprusside therapy. The preferred test for this would be Thiocyanate.

Lab Testing Sections:

Chemistry - Sendouts

Referred to:

Mayo Medical Laboratories (MML Test: 8691/CYAN)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

1 – 4 days, test set up Monday, Wednesday and Friday (5pm)

Special Instructions:

N/A

Specimen

Specimen Type:

Whole blood

Container:

Lavender top (EDTA) tube

Draw Volume:

3 mL (Minimum: 1.5 mL) blood

Processed Volume:

Same as Draw Volume

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Do Not centrifuge. Send as whole blood in original collection container. Store and ship at ambient temperatures. Forward promptly.

Patient Preparation:

None

Sample Rejection:

Specimens other than whole blood; mislabeled or unlabeled specimens

Interpretive

Reference Range:

Normal: <0.2 mcg/mL

This test was developed and its performance characteristics determined by Laboratory Medicine and Pathology, Mayo Clinic. This test has not been cleared or approved by the US Food and Drug Administration.

Critical Values:

Toxic concentration: ≥2.0 mcg/mL

Limitations:

Concentrations as high as 8.0 mcg/mL without symptoms of cyanide toxicity are commonly associated with nitroprusside therapy; one should monitor thiocyanate to determine the potential for intoxication during nitroprusside therapy for hypertensive crisis.

Methodology:

Colorimetric

References:

Mayo Medical Laboratories (October 2014)

Updates:

7/12/2010: Units update from ug/mL to mcg/mL.



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