Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

DHEA-S

General Information

Lab Order Codes:

DHES

Synonyms:

Dehydroepiandrosterone Sulfate; DHEA Sulfate

CPT Codes:

82627 - Dehydroepiandrosterone Sulfate

Test Includes:

DHEA-S level reported in ug/dL.

Logistics

Test Indications:

Used to work up women with infertility, amenorrhea, or hirsutism, to identify the source of excessive androgen. Aid in evaluation of androgen excess (hirsutism and/or virilization), including congenital adrenal hyperplasia, adrenal tumor, and Stein - Leventhal syndrome. DHEA-S is not increased with hypopituitarism. It is low in Addison’s disease.

Lab Testing Sections:

Chemistry - Sendouts

Referred to:

Esoterix, Inc. (Lab Corp Test: 500120)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

4 - 7 days, test set up Monday - Saturday

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Red top tube

Draw Volume:

1.5 mL (Minimum: 0.3 mL) blood

Processed Volume:

0.5 mL (Minimum 0.1 mL) serum
Note:
Minimum volume does not permit repeat analysis.

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen within 1 hour of collection. Remove serum aliquot into a screw-capped round bottom plastic vial. Store and ship at frozen temperatures. Forward promptly.

Patient Preparation:

Avoid recently administered radioisotopes

Sample Rejection:

Recently administered radioisotopes; unlabeled or mislabeled specimens

Interpretive

Reference Range:

Premature Infants:

26 – 28 weeks, Day 4:

123 – 882 ug/dL

31 – 35 weeks, Day 4:

122 – 710 ug/dL

Full Term Infants:

3 days:

88 – 356 ug/dL

1 – 11 months

DHEA-S levels fall to <112 ug/dL during the first month and decrease further to <49 ug/dL by 6 months of age.

Prepubertal Children:

1 – 5 years:

<57 ug/dL

6 – 7 years:

<72 ug/dL

8 – 10 years:

<193 ug/dL

Puberty:

 

MALE

FEMALE

Tanner Stage

Age (years)

Range (ug/dL)

Age (years)

Range (ug/dL)

1

<9.8

13 – 83

<9.2

19 – 144

2

9.8 – 14.5

42 – 109

9.2 – 13.7

34 – 129

3

10.7 – 15.4

48 – 200

10.0 – 14.4

32 – 226

4

11.8 – 16.2

102 – 385

10.7 – 15.6

58 – 260

5

12.8 – 17.3

120 – 370

11.8 – 18.6

44 – 248

Adults:

 

MALE

FEMALE

Age

Range (ug/dL)

Range (ug/dL)

21 – 30 years

38 – 523

22 – 372

31 – 40 years

33 – 416

17 – 286

41 – 50 years

16 – 390

<229

51 – 60 years

<298

<215

61 – 70 years

<251

<128

71 – 80 years

<208

<111

81 – 90 years

<106

<101

Critical Values:

N/A

Limitations:

N/A

Methodology:

HPLC, Tandem Mass Spectrometry

References:

Esoterix, Inc. Web Page June 2013



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