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Lab Dept:
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Chemistry
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Test Name:
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INTERLEUKIN-2 RECEPTOR
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General Information
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Lab Order Codes:
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IL2R
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Synonyms:
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IL 2 Receptor
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CPT Codes:
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84238 – Receptor assay, non-endocrine
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Test Includes:
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Interleukin-2 Receptor level reported in U/mL.
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Logistics
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Test Indications:
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Clinical conditions in which elevated soluble IL-2R levels are detected include AIDS, autoimmune disease, sarcoidosis, and a variety of leukemias and lymphomas. In HIV positive individuals, IL-2R is elevated during the asymptomatic phase as well as during persistent generalized lymphadenopathy and symptomatic phases. IL-2R detection may be useful in measuring T cell activation and monitoring HIV pathogenesis. Elevated IL-2R levels have clinical and prognostic significance in patients with malignant lymphoma, non-Hodgkin’s lymphoma, B cell and undifferentiated lymphomas.
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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Mayo Medical Laboratories forward to Focus Technologies (Test# 90021/FIL2R)
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Phone Numbers:
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MIN Lab: 612-813-6280
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STP Lab: 651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1 - 9 days
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Special Instructions:
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N/A
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Specimen
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Specimen Type:
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Blood
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Container:
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Red top tube
Alternate tubes: Green top (Heparin), Lavender top (EDTA) and Yellow (ACD) tubes
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Draw Volume:
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6 mL (Minimum: 1.5 mL) blood
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Processed Volume:
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2 mL (Minimum: 0.5 mL) serum/plasma
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Centrifuge specimen and separate serum/plasma aliquot into a screw-capped round bottom plastic vial. Store and ship at frozen temperatures. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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<970 U/mL
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Critical Values:
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N/A
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Limitations:
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This assay is performed using a kit labeled “For Research Use Only” by the kit manufacturer. The kit’s performance characteristics have been established and validated by Focus Diagnostics for in-vitro diagnostic use.
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Methodology:
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Enzyme-linked Immunosorbent Assay (ELISA)
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References:
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Mayo Medical Laboratories Web Page January 2013
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Focus Diagnostics Web Page January 2013
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Updates:
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3/18/2004: Test moved from Specialty Laboratories to Mayo Medical Laboratories forward to Focus Technologies. Note changes in CPT code, Methodology, and reference range.
9/16/2008: CPT update, previously reported at 83520
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