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Lab Dept:
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Chemistry
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Test Name:
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LYSOZYME
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General Information
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Lab Order Codes:
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LYSO
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Synonyms:
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Lysozyme (Muramidase), Plasma
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CPT Codes:
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85549 - Muramidase
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Test Includes:
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Lysozyme (Muramidase) level reported in µg/mL.
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Logistics
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Test Indications:
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Useful for confirming marked increase in the granulocyte or monocyte pool as in granulocytic or monocytic leukemias, myeloproliferative disorders, and malignant histiocytosis and in following the course of therapy in cases of chronic granulocytic or chronic monocytic leukemias.
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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Mayo Medical Laboratories (Test# 8507)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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2 - 5 days, test set up Monday - Friday
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Special Instructions:
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N/A
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Specimen
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Specimen Type:
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Blood
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Container:
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Lavender top (EDTA) tube
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Draw Volume:
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6 mL (Minimum: 3 mL) blood
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Processed Volume:
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2 mL (Minimum: 1 mL) plasma
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Centrifuge specimen, remove plasma aliquot into a screw-capped round bottom plastic vial. Store and ship at frozen temperatures. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Specimens other than plasma, warm specimens, unlabeled or mislabeled specimens
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Interpretive
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Reference Range:
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2.7 – 9.4 mcg/mL
Note: Levels >200 µg/mL may be seen in acute nonlymphocytic leukemia (M2, M4, M5) or chronic granulocytic leukemias.
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Critical Values:
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N/A
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Limitations:
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Increased levels may be seen in nonmalignant disorders including infections, Crohn’s disease, kidney transplant rejection, and other renal disorders.
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Methodology:
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Turbidimetric
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References:
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Mayo Medical Laboratories August 2010
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Updates:
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8/25/2010: Units changed from ug/mL to mcg/mL. Reference range update.
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