Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

VASOACTIVE INTESTINAL POLYPEPTIDE

General Information

Lab Order Codes:

VIPP

Synonyms:

Vasoactive Intestinal Polypeptide (VIP), Plasma

CPT Codes:

84586 - Vasoactive Intestinal Polypeptide

Test Includes:

VIP level reported in pg/mL.

Logistics

Test Indications:

Useful for detection of VIPoma in patients with chronic diarrheal diseases.

Lab Testing Sections:

Chemistry - Sendouts

Referred to:

Mayo Medical Laboratories (MML Test: 8150/VIP)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

3 – 8 days, test set up Monday and Wednesday

Special Instructions:

See Patient Preparation below

Specimen

Specimen Type:

Whole blood

Container:

Lavender top (EDTA) tube

Draw Volume:

3 mL (Minimum: 1.7 mL) blood

Processed Volume:

1 mL (Minimum: 0.55 mL) plasma

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen immediately, remove plasma aliquot into a screw-capped round bottom plastic vial. Store and ship at frozen temperatures. Forward promptly.

Patient Preparation:

This test should not be requested on patients who have recently received radioactive material. Patient should be fasting (recommended 8 hours).

Sample Rejection:

Gross hemolysis; gross lipemia; mislabeled or unlabeled specimens

Interpretive

Reference Range:

<75 pg/mL

Interpretation: Values >75 pg/mL may indicate presence of enteropancreatic tumor causing hypersection of vasoactive intestinal polypeptide (VIP).

Values >200 pg/mL are strongly suggestive of VIP producing tumors (VIPoma). VIPoma is unlikely with 24 hour stool volume <700 mL.

Critical Values:

N/A

Limitations:

This test should not be performed on patients who have recently received radioactive material.

Methodology:

Radioimmunoassay (RIA)

References:

Mayo Medical Laboratories July 2013



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