Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

TSH RECEPTOR ANTIBODY

General Information

Lab Order Codes:

THYS

Synonyms:

Thyroid Stimulating Hormone (TSH) Receptor Antibody, Serum; TRAb

CPT Codes:

84445 – Thyroid stimulating immune globulins (TSI)

Test Includes:

N/A

Logistics

Test Indications:

Thyroid receptor antibodies are elevated in patients with Graves' disease and autoimmune thyroiditis. Thyroid receptor antibodies are not found in the normal population. TRAb are present in more than 90% of patients with active Graves' disease. TSI activity is present in approximately 80% of patients with Graves' disease. Some sera potent in TRAb activity display no TSI activity, and apparently the reverse is also the case.

Lab Testing Sections:

Chemistry - Sendouts

Referred to:

Esoterix, Inc. (Test: 500308)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

2 - 3 days, Test set up Tuesday and Thursday

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Red top (plain, no gel) tube

Draw Volume:

3 mL (Minimum: 0.6 mL) blood

Processed Volume:

1 mL (Minimum: 0.2 mL) serum

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen within 1 hour of collection, remove serum aliquot into a screw-capped round bottom plastic vial. Store and ship at frozen temperatures. Forward promptly.

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimens

Interpretive

Reference Range:

TSH Binding Inhibition Index

<10

Normal

10 - 14

Indeterminate

>14

Positive

Critical Values:

N/A

Limitations:

N/A

Methodology:

Binding inhibition assay

References:

Esoterix Inc. Web Page www.esoterix.com July 2012

Esoterix Inc “Expected Values and S.I. Unit Conversion Tables”, Fifth Edition, 2003



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