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Lab Dept:
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Chemistry
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Test Name:
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TSH RECEPTOR ANTIBODY
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General Information
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Lab Order Codes:
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THYS
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Synonyms:
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Thyroid Stimulating Hormone (TSH) Receptor Antibody, Serum; TRAb
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CPT Codes:
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84445 – Thyroid stimulating immune globulins (TSI)
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Test Includes:
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N/A
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Logistics
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Test Indications:
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Thyroid receptor antibodies are elevated in patients with Graves' disease and autoimmune thyroiditis. Thyroid receptor antibodies are not found in the normal population. TRAb are present in more than 90% of patients with active Graves' disease. TSI activity is present in approximately 80% of patients with Graves' disease. Some sera potent in TRAb activity display no TSI activity, and apparently the reverse is also the case.
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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Esoterix, Inc. (Test# 500308)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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2 - 3 days, Test set up Tuesday and Thursday
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Special Instructions:
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N/A
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Specimen
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Specimen Type:
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Blood
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Container:
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Red top (plain, no gel) tube
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Draw Volume:
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3 mL (Minimum: 0.6 mL) blood
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Processed Volume:
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1 mL (Minimum: 0.2 mL) serum
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Centrifuge specimen within 1 hour of collection, remove serum aliquot into a screw-capped round bottom plastic vial. Store and ship at frozen temperatures. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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TSH Binding Inhibition Index
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<10
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Normal
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10 - 14
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Indeterminate
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>14
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Positive
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Critical Values:
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N/A
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Limitations:
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N/A
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Methodology:
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Binding inhibition assay
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References:
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Esoterix Inc. Web Page www.esoterix.com July 2012
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Esoterix Inc “Expected Values and S.I. Unit Conversion Tables”, Fifth Edition, 2003
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