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Lab Dept:
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Chemistry
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Test Name:
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MEDIUM CHAIN ACYL-CO-A DEHYDROGENASE
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General Information
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Lab Order Codes:
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MCAD
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Synonyms:
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Medium Chain Acyl-Co-A Dehydrogenase (Mutation Analysis)
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CPT Codes:
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83912 – Molecular diagnostics; interpretation and report
83898 - Amplification of nucleic acid, single primer pair
83890 - Molecular diagnostics; molecular isolation
83894 - Separation by gel electrophoresis
83892 – Molecular diagnostics; enzymatic digestion
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Test Includes:
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An interpretive report will be provided.
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Logistics
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Test Indications:
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Useful for determining the homozygousity (affected patient’s) and heterozygousity (carriers) of the 985 mutation for MCAD. This mutation is the most common, accounting for approximately 89% of the mutant alleles
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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Fairview University Diagnostic Laboratories (Test# MCAD)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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Performed once per week, results reported the next day
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Special Instructions:
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Request special collection tube from the laboratory. See Container
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Specimen
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Specimen Type:
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Whole blood
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Container:
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Yellow top (ACD, Solution A) tube
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Draw Volume:
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10 mL (Minimum: 5 mL) blood
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Processed Volume:
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Same as Draw Volume
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Do Not Centrifuge. Submit specimen intact in original collection container. Store in refrigerator. Ship at ambient temperatures. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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An interpretation is provided with each report.
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Critical Values:
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N/A
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Limitations:
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N/A
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Methodology:
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Amplification of DNA and electrophoresis
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References:
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Fairview-University Diagnostic Laboratories Web Page http://labguide.fairview.org/diagnostic.asp July 2012
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