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Lab Dept:

Chemistry

Test Name:

17-OH PREGNENOLONE, SERUM

General Information

Lab Order Codes:

17O

Synonyms:

Hydroxypregnenolone 17-; Pregnenolone 17OH

CPT Codes:

84143 – 17- hydroxypregnenolone

Test Includes:

N/A

Logistics

Test Indications:

Assessment of 3-beta-OH steroid dehydrogenase deficiency, a form of congenital adrenal hyperplasia. Assessment of presence an adrenal virilizing tumor.

Lab Testing Sections:

Chemistry - Sendouts

Referred to:

Esoterix, Inc. (Test# 500262)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

3 - 6 days

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Red top tube

Draw Volume:

3 mL (Minimum: 0.3 mL) blood

Processed Volume:

1 mL (Minimum: 0.1 mL) serum

Note: Minimum volume does not permit repeat analysis.

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen within 1 hour of collection. Remove serum aliquot into a screw-capped round bottom plastic vial. Store and ship at frozen temperatures. Forward promptly.

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimens

Interpretive

Reference Range:

Age:

Range (ng/dL)

Premature Infants:

26-28 weeks, day 4:

375 - 3559

31 – 35 weeks, day 4:

64 - 2380

Full Term Infants:

3 days:

10 - 829

1 – 5 months:

36 - 763

6 – 11 months:

42 - 540

Prepubertal Children:

12 - 23 months:

14 - 207

24 months – 5 years:

10 - 103

6 – 9 years:

10 - 186

Pubertal Age Groups:

44 - 235

Adults:

53 - 357

Critical Values:

N/A

Limitations:

N/A

Methodology:

HPLC Tandem Mass Spectrometry

References:

Esoterix, Inc. Web Page www.esoterix.com

Updates:

9/29/2009: Method, reference range update



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