Lab Dept:

Chemistry

Test Name:

17-OH PROGESTERONE, SERUM

General Information

Lab Order Codes:

17OHP

Synonyms:

Hydroxyprogesterone 17; Progesterone 17-OH; 17OHP

CPT Codes:

84143 – 17-Hydroxypregnenolone

Test Includes:

17 OHP level reported in ng/dL.

Logistics

Test Indications:

Marker for adrenal (21-hydroxylase) enzyme deficiency

Lab Testing Sections:

Chemistry - Sendouts

Referred to:

Esoterix, Inc. (Test# 500270)

Phone Numbers:

Minneapolis:

Saint Paul:

612-813-6280

651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

5 - 8 days, performed Tuesday, Thursday and Saturday

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Red top tube

Draw Volume:

3 mL (Minimum: 0.3 mL) blood

Processed Volume:

1 mL (Minimum: 0.1 mL) serum

Note: Minimum volume does not permit repeat analysis.

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen within 1 hour of collection. Remove serum aliquot into a screw-capped round bottom plastic vial. Store and ship at frozen temperatures. Forward promptly.

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimens

Interpretive

Reference Range:

Premature Infants:

26 – 28 weeks, day 4

124 – 841 ng/dL

31 – 35 weeks, day 4

26 – 568 ng/dL

Full Term Infants:

3 days

7 – 77 ng/dL

1 – 11 months

Male:

Female:

Levels increase after the first week to peak values ranging from 40 – 200 ng/dL between 30 and 60 days. Values then decline to Prepubertal range for 1 year.

13 – 106 ng/dL

Prepubertal Children:

1 – 10 years:

3 – 90 ng/dL

Puberty:

Male:

Female

Tanner Stage:

Age (yrs)

Range ng/dL

Age (yrs)

Range ng/dL

1

<9.8

3 – 90
Mean: 38

<9.2

3 – 82
Mean: 31

2

9.8 – 14.5

5 – 115
Mean: 51

9.2 – 13.7

11 - 98
Mean: 49

3

10.7 – 15.4

10 - 138
Mean: 57

10.0 – 14.4

11 - 155
Mean: 70

4

11.8 – 16.2

29 - 180
Mean: 80

10.7 – 15.6

18 - 230
Mean: 91

5

12.8 – 17.3

24 – 175
Mean: 97

11.8 – 18.6

20 - 265
Mean: 108

Adults:

Male:

Female:

29 – 199 ng/dL

Follicular:

15 – 70 ng/dL

Luteal:

35 – 290 ng/dL

Critical Values:

N/A

Limitations:

N/A

Methodology:

HPLC tandem mass spectrometry

References:

Esoterix, Inc. Web Page April 2010

Updates:

9/29/2009: Updated method, reference values
5/5/2010: Updated CPT code.