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Lab Dept:
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Chemistry
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Test Name:
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HEAVY METALS SCREEN, BLOOD
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General Information
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Lab Order Codes:
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HMSB
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Synonyms:
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Arsenic, blood; Cadmium, blood; Lead, blood; Mercury, blood; Metals Screen, blood
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CPT Codes:
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82175 – Arsenic
82300 – Cadmium
83655 –Lead
83825 - Mercury
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Test Includes:
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Arsenic (ng/mL), cadmium (ng/mL), lead (mcg/dL), and mercury (ng/mL)
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Logistics
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Test Indications:
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Mayo Medical Laboratories offers both an essential elements screen and a heavy metals screen. In the case when a metals screen is ordered, we will assume this to be a heavy metals screen request, the specimen will be retained for 2 weeks following testing during which time you may call and request other testing. Contact Children’s laboratory for additional test requests.
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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Mayo Medical Laboratories (Test# 15080)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1 - 3 days, test set up Monday - Saturday
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Special Instructions:
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Obtain special collection tube from the laboratory. See Container. See Collection.
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Specimen
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Specimen Type:
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Whole blood
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Container:
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Obtain this collection device from the lab:
Royal Blue top, Trace element (EDTA) tube - Mayo Supply #T183
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Draw Volume:
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2.5 mL (Minimum: 1 mL) blood
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Processed Volume:
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Same as Draw Volume
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Collection:
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Preferred collection - Royal Blue top, trace element tube: Draw blood into a royal blue top Monoject trace element blood collection tube (Mayo supply #T183), containing EDTA as an anticoagulant. Blood must be drawn directly into the tube with the use of a butterfly needle or other stainless steel needle by vacutainer technique. The royal blue tube must be the first tube collected to prevent contamination. Mix gently.
EDTA BD microtainer: Perform a fingerstick for this testing. Heavy Metals and Zinc can be collected via fingerstick by collecting 0.5 mL. If drawing other tubes, please collect this one first. The metals tube cannot be shared with other EDTA related testing (ie, CBC) and will only be used for the metals testing. Mix gently.
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Special Processing:
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Lab Staff: Do Not Centrifuge. Send specimen in original collection container. Store and ship at refrigerated temperatures. Make sure to result demographic information prior to sending specimen. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Green top (heparin) tube is not acceptable, anticoagulants other than EDTA, specimens other than blood, mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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Lead
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0 – 6 years:
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0 – 4 mcg/mL
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> or = 7years:
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0 – 9 mcg/dL
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Arsenic
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All ages:
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0 – 12 ng/mL
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Cadmium
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All ages:
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0.0 – 4.9 ng/mL
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Mercury
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Mercury: All ages
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<10 ng/mL
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Critical Values:
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Lead: ≤15 years:
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≥20 mcg/dL
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Lead: Adult (≥16 yrs)
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≥70 mcg/dL
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Limitations:
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Gadolinium is known to interfere with most metals tests. If gadolinium-containing contrast media has been administered, a specimen cannot be collected for 48 hours.
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Methodology:
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Inductively Coupled Plasma/Mass Spectrometry (ICP-MS)
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Contraindications:
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Specimens collected in containers other than those recommended are subject to contamination which may result in falsely elevated values.
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References:
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Mayo Medical Laboratories Web Page (November 2010)
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Updates:
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3/24/2008: Metal-free syringes are not available for collection. Use vacutainer or finger stick option into a microtainer.
8/18/2009: Units for Lead changed from ug/dL to mcg/dL. Units for Arsenic changed from ug/mL to mcg/mL.
11/17/2010: Arsenic units changed from mcg/mL to ng/mL. Toxic level for Mercury removed. All reference ranges updated.
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