|
|
|
Lab Dept:
|
Chemistry
|
Test Name:
|
AMMONIA
|
General Information
|
Lab Order Codes:
|
NH3
|
Synonyms:
|
NH3
|
CPT Codes:
|
82140 – Ammonia
|
Test Includes:
|
Ammonia concentration reported in umol/L
|
Logistics
|
Test Indications:
|
Hyperammonemia may result from several causes, both inherited and acquired. The inherited deficiencies of urea cycle enzymes are the major cause of hyperammonemia in infants. The acquired causes include advanced liver disease and renal failure. Reye’s Syndrome is also associated with high ammonia levels.
|
Lab Testing Sections:
|
Chemistry
|
Phone Numbers:
Minneapolis:
Saint Paul:
|
|
612-813-6280
|
651-220-6550
|
Test Availability:
|
Daily, 24 hours
|
Turnaround Time:
|
1 hour
|
Special Instructions:
|
Specimen should be transported to the lab on wet ice within 5 minutes of collection.
|
Specimen
|
Specimen Type:
|
Blood
|
Container:
|
Green top (Li Heparin) tube
|
Draw Volume:
|
0.6 mL blood
|
Processed Volume:
|
0.2 mL plasma
|
Collection:
|
Venipuncture only, atraumatic draw. The collection tube should be completely filled, tightly capped, gently inverted to mix and placed on wet ice. Specimen should be transported to the lab on wet ice within 5 minutes of collection.
|
Special Processing:
|
Lab Staff: The specimen should be centrifuged, plasma aliquot removed to a plastic sample cup and tested within 20 minutes of collection. Specimens that cannot be tested immediately should be frozen.
|
Patient Preparation:
|
Patient should avoid smoking prior to sampling.
|
Sample Rejection:
|
Clotted specimens; mislabeled specimens; fingerstick specimens; hemolyzed specimens; specimens not received on ice
|
Interpretive
|
Reference Range:
|
Age
|
Range (umol/L)
|
0 – 13 days:
|
64 – 107
|
14 days – 1 month:
|
56 – 92
|
1 month – 18 years:
|
21 – 50
|
>18 years:
|
11 - 32
|
Critical Values:
|
>150 umol/L
|
Limitations:
|
N/A
|
Methodology:
|
Glutamate Dehydrogenase
|
References:
|
AMON Flex® reagent cartridge insert sheet PN 717019.001 Issue Date 2010-10-26 Rev. K
|
Clinical Significance, Dade Behring Inc., Glasgow Business Community, Mailbox 531, P.O. Box 6101, Newark, Delaware 19714
|
Burtis, CA and Ashwood, ER (1999) Tietz Textbook of Clinical Chemistry, 3rd Edition, Philadelphia, PA: WB Saunders Co., p 1146-7.
|
Jacobs & DeMott Laboratory Test Handbook, Lexi-Comp, Inc, Hudson, OH, 5th Edition, 2001
|
Biorad Liquichek Ethanol/Ammonia Control Product Insert, Bio-Rad Laboratories, Irvine, CA 92618
|
Updates:
|
8/29/2005: TAT previously listed as 4 hours.
|
