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Lab Dept:
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Chemistry
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Test Name:
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CREATINE KINASE
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General Information
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Lab Order Codes:
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CPK
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Synonyms:
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CK; Creatine Phosphokinase; CPK
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CPT Codes:
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82550 – Creatine kinase (CK), (CPK), total
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Test Includes:
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Creatine Kinase concentration reported in U/L.
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Logistics
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Test Indications:
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Creatine kinase activity is useful in evaluating diseases of the heart, skeletal muscle, and brain.
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Lab Testing Sections:
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Chemistry
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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2 hours
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Special Instructions:
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N/A
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Specimen
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Specimen Type:
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Blood
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Container:
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Green top (Li Heparin) tube preferred
Alternate tube: Red top (plain, no gel) tube
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Draw Volume:
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0.6 mL blood
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Processed Volume:
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0.2 mL serum/plasma
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Collection:
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Routine venipuncture. Mix tubes containing anticoagulant by gentle inversion.
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Special Processing:
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Lab Staff: Centrifuge specimen, remove serum/plasma aliquot into plastic sample cup. Analyze sample immediately or store at refrigerated temperatures.
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Patient Preparation:
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None
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Sample Rejection:
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Mislabeled or unlabeled specimen
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Interpretive
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Reference Range:
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21 – 232 U/L
Note: Strenuous exercise or intramuscular injections may cause transient elevations of CK.
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Critical Values:
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>4000 U/L
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Limitations:
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CK concentration is increased by excess hemolysis in the patient sample, and decreased by excess bilirubin.
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Methodology:
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Enzymatic, 37°C
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References:
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Jacobs and DeMott Laboratory Test Handbook (2001) Lexi-Comp, Inc., Hudson, OH, 5th ed
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CKI Flex reagent cartridge insert sheet (08-28-2008) PN 717038.001- Rev. B
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Updates:
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7/10/2007: Critical value added.
12/22/2011: Turnaround time updated, previously listed as 4 hours.
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