Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

CREATINE KINASE

General Information

Lab Order Codes:

CPK

Synonyms:

CK; Creatine Phosphokinase; CPK

CPT Codes:

82550 – Creatine kinase (CK), (CPK), total

Test Includes:

Creatine Kinase concentration reported in U/L.

Logistics

Test Indications:

Creatine kinase activity is useful in evaluating diseases of the heart, skeletal muscle, and brain.

Lab Testing Sections:

Chemistry

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

2 hours

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Green top (Li Heparin) tube preferred
Alternate tube: Red top (plain, no gel) tube

Draw Volume:

0.6 mL blood

Processed Volume:

0.2 mL serum/plasma

Collection:

Routine venipuncture. Mix tubes containing anticoagulant by gentle inversion.

Special Processing:

Lab Staff: Centrifuge specimen, remove serum/plasma aliquot into plastic sample cup. Analyze sample immediately or store at refrigerated temperatures.

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimen

Interpretive

Reference Range:

21 – 232 U/L

Note: Strenuous exercise or intramuscular injections may cause transient elevations of CK.

Critical Values:

>4000 U/L

Limitations:

CK concentration is increased by excess hemolysis in the patient sample, and decreased by excess bilirubin.

Methodology:

Enzymatic, 37C; IFCC Standardized

References:

Jacobs and DeMott Laboratory Test Handbook (2001) Lexi-Comp, Inc., Hudson, OH, 5th ed

Siemens Dimension Vista CKI Flex Insert PN 781038.001, REV B, 10/1/2012

Updates:

7/10/2007: Critical value added.
12/22/2011: Turnaround time updated, previously listed as 4 hours.



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