Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

VANCOMYCIN LEVEL, SERUM

General Information

Lab Order Codes:

VANC

Synonyms:

Vancocin®

CPT Codes:

80202 - Vancomycin

Test Includes:

Vancomycin concentration in ug/mL

Logistics

Test Indications:

Useful for therapeutic drug monitoring (TDM). Vancomycin is a glycopeptide that is a bactericidal agent against gram-positive bacteria and some gram-negative cocci. Vancomycin is important in the treatment of cephalosporin and methicillin-resistant organisms.

Lab Testing Sections:

Chemistry

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

4 hours

Special Instructions:

Peak levels should be drawn 20-60 minutes after infusion. Trough levels should be drawn within 30 minutes prior to giving a subsequent dose.

Specimen

Specimen Type:

Blood

Container:

Green top (Li Heparin) tube preferred
Alternate: Red top (plain, no gel) tube

Draw Volume:

0.6 mL blood

Processed Volume:

0.2 mL serum/plasma

Collection:

Routine venipuncture. Mix tubes containing anticoagulant by gentle inversion. See Special Instructions regarding peak/trough information.

Special Processing:

Lab Staff: Centrifuge specimen, remove serum/plasma aliquot into plastic sample cup. Store at refrigerated temperatures.

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimen

Interpretive

Reference Range:

Peak Values:

Therapeutic concentration:

30 - 40 ug/mL

Trough Values:

Therapeutic concentration:

<5 - 10 ug/mL

Critical Values:

Peak Values:

Toxic concentration:

>50 ug/mL

Trough Values:

Toxic concentration:

>50 ug/mL

Limitations:

N/A

Methodology:

Particle Enhanced Turbidimetric Inhibition Immunoassay (PETINIA)

References:

VANC Flex® reagent cartridge insert sheet (2009-05-27) Siemens Healthcare Diagnostics Inc, PN 717086.001 – US, Rev F

www.childrensmn.org/Lexi-Comp Copyright © 1978-2006 Lexi-Comp Inc.

Clinical Significance, Dade Behring Inc., Glasgow Business Community, Mailbox 531, P.O. Box 6101, Newark, Delaware 19714

Jacobs & DeMott Laboratory Test Handbook (2001) Lexi-Comp, Inc, Hudson, OH, 5th Edition

Biorad Liquichek Unassayed Chemistry Control Product Insert, Bio-Rad Laboratories, Irvine, CA 92618



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