Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

IRON/TIBC

General Information

Lab Order Codes:

FEPR (Total Iron, Total Iron Binding Capacity and % Saturation)

FE (Total Iron Only)

TIBC (Total Iron Binding Capacity Only)

Synonyms:

Iron and Total Iron - Binding Capacity, FE, IBC, TIBC

CPT Codes:

83540 – Iron
83550 – Iron binding capacity

Test Includes:

Includes total iron (ug/dL), total iron binding capacity (ug/dL), and percent iron saturation.
Note:
If total iron only or Total Iron Binding Capacity Only is ordered only that particular test will be performed.

Logistics

Test Indications:

Useful for the diagnosis of anemia and to evaluate iron toxicity (from ingestion). Iron deficiency and iron overload are the major disorders of iron metabolism, however, altered iron metabolism has been observed or shown to be related to a number of other diseases including anemia, cardiovascular disease, chronic hepatitis, end-stage renal disease, HIV infection, and other infections.

Lab Testing Sections:

Chemistry

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

4 hours, Stat: 2 hours

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Red top tube

Draw Volume:

1 mL blood

Processed Volume:

0.3 mL serum

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen, remove serum aliquot into plastic sample cup. Analyze specimen immediately or store at refrigerated temperatures.

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimen; specimens other than serum; gross hemolysis

Interpretive

Reference Range:

Iron

0 – 2 months:

100 – 250 ug/dL

2 months – 2 years:

40 – 100 ug/dL

2 years – adult:

50 – 120 ug/dL

Total Iron Binding Capacity

0 – 2 years:

100 – 400 ug/mL

>2 years:

250 – 400 ug/mL

Percent Saturation

11 - 46%

Critical Values:

N/A

Limitations:

Hemolysis elevates the serum iron. Excess bilirubin in the patient sample decreases serum iron. Some medications containing iron may increase TIBC values.

Methodology:

Ferene

References:

Reference: IRON Flex® reagent cartridge insert sheet PN 717085.001 (Issue Date 2009-05-15) Rev. C

Clinical Significance, Dade Behring Inc., Glasgow Business Community, Mailbox 531, P.O. Box 6101, Newark, Delaware 19714

Jacobs & DeMott Laboratory Test Handbook (2001) Lexi-Comp, Inc, Hudson, OH, 5th Edition

Biorad Liquichek Unassayed Chemistry Control Product Insert (10/2005) Bio-Rad Laboratories, Irvine, CA 92618



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