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Lab Dept:
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Chemistry
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Test Name:
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LACTATE DEHYDROGENASE (LD)
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General Information
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Lab Order Codes:
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LDH
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Synonyms:
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LDH; LD
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CPT Codes:
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83615 – Lactate Dehydogenase
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Test Includes:
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Lactate dehydrogenase concentration reported in U/L.
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Logistics
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Test Indications:
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Lactate dehydrogenase is an enzyme that is found in almost all body tissues. LD is used as a general marker of injury to cells. LD is used to diagnose myocardial infarction, hepatic congestion, severe shock, renal disease, progressive muscular dystrophy, and pulmonary embolism.
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Lab Testing Sections:
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Chemistry
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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4 hours
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Special Instructions:
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N/A
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Specimen
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Specimen Type:
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Blood
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Container:
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Green top (Li Heparin) tube preferred
Alternate tube: Red top (plain, no gel) tube
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Draw Volume:
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0.6 mL blood
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Processed Volume:
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0.2 mL serum/plasma
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Collection:
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Routine venipuncture. Mix tubes containing anticoagulant by gentle inversion.
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Special Processing:
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Lab Staff: Centrifuge specimen, remove serum/plasma aliquot into a plastic sample cup. Store at refrigerated temperatures.
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Patient Preparation:
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None
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Sample Rejection:
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Mislabeled or unlabeled specimen; specimens other than heparinized plasma or serum; grossly hemolyzed specimen
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Interpretive
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Reference Range:
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Age
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Range (U/L)
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0 - 1 day:
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356 - 2236 U/L
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1 day - 6 weeks:
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238 - 1242 U/L
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6 weeks - 18 months:
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250 - 568 U/L
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18 months - 3 years:
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299 - 484 U/L
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3 - 8 years:
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229 - 457 U/L
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8 - 11 years:
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224 - 390 U/L
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11 - 14 years:
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173 - 379 U/L
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14 - 16 years:
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155 - 335 U/L
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>16 years:
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119 - 248 U/L
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Critical Values:
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N/A
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Limitations:
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LD concentrations are increased by excess hemolysis.
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Methodology:
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Enzymatic, 37° C
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References:
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LDI Flex® reagent cartridge insert sheet PN 717054.001 (Issue Date 2009-08-17) Rev. B
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Clinical Significance, Dade Behring Inc., Glasgow Business Community, Mailbox 531, P.O. Box 6101, Newark, Delaware 19714
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Jacobs & DeMott Laboratory Test Handbook (2001) Lexi-Comp, Inc, Hudson, OH, 5th Edition
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Biorad Liquichek Unassayed Chemistry Control Product Insert (10/2005) Bio-Rad Laboratories, Irvine, CA 92618
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