Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

LACTATE DEHYDROGENASE (LD)

General Information

Lab Order Codes:

LDH

Synonyms:

LDH; LD

CPT Codes:

83615 – Lactate Dehydogenase

Test Includes:

Lactate dehydrogenase concentration reported in U/L.

Logistics

Test Indications:

Lactate dehydrogenase is an enzyme that is found in almost all body tissues. LD is used as a general marker of injury to cells. LD is used to diagnose myocardial infarction, hepatic congestion, severe shock, renal disease, progressive muscular dystrophy, and pulmonary embolism.

Lab Testing Sections:

Chemistry

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

4 hours

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Green top (Li Heparin) tube preferred
Alternate tube: Red top (plain, no gel) tube

Draw Volume:

0.6 mL blood

Processed Volume:

0.2 mL serum/plasma

Collection:

Routine venipuncture. Mix tubes containing anticoagulant by gentle inversion.

Special Processing:

Lab Staff: Centrifuge specimen, remove serum/plasma aliquot into a plastic sample cup. Store at refrigerated temperatures.

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimen; specimens other than heparinized plasma or serum; grossly hemolyzed specimen

Interpretive

Reference Range:

Age

Range (U/L)

0 - 1 day:

356 - 2236 U/L

1 day - 6 weeks:

238 - 1242 U/L

6 weeks - 18 months:

250 - 568 U/L

18 months - 3 years:

299 - 484 U/L

3 - 8 years:

229 - 457 U/L

8 - 11 years:

224 - 390 U/L

11 - 14 years:

173 - 379 U/L

14 - 16 years:

155 - 335 U/L

>16 years:

119 - 248 U/L

Critical Values:

N/A

Limitations:

LD concentrations are increased by excess hemolysis.

Methodology:

Enzymatic, 37° C

References:

LDI Flex® reagent cartridge insert sheet PN 717054.001 (Issue Date 2009-08-17) Rev. B

Clinical Significance, Dade Behring Inc., Glasgow Business Community, Mailbox 531, P.O. Box 6101, Newark, Delaware 19714

Jacobs & DeMott Laboratory Test Handbook (2001) Lexi-Comp, Inc, Hudson, OH, 5th Edition

Biorad Liquichek Unassayed Chemistry Control Product Insert (10/2005) Bio-Rad Laboratories, Irvine, CA 92618



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