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Lab Dept:
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Chemistry
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Test Name:
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THEOPHYLLINE LEVEL
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General Information
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Lab Order Codes:
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THEO
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Synonyms:
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Aminophylline; Theodur; Slo-Bid
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CPT Codes:
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80198 - Theophylline
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Test Includes:
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Theophylline concentration reported in ug/mL.
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Logistics
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Test Indications:
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Theophylline relaxes bronchial smooth muscles to relieve or prevent asthma. Caffeine is a minor metabolite and is often seen in neonates taking theophylline. Peak levels are achieved in 30–90 minutes depending on the compound and type of preparation. The biologic half-life ranges from 3.5 hours in young children to 8–9 hours in adults.
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Lab Testing Sections:
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Chemistry
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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2 hours
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Special Instructions:
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N/A
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Specimen
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Specimen Type:
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Blood
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Container:
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Green top (Li Heparin) tube preferred
Alternate tube: Red top (plain, no gel) tube
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Draw Volume:
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0.6 mL blood
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Processed Volume:
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0.2 mL serum/plasma
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Collection:
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Routine venipuncture. Mix tubes containing anticoagulant by gentle inversion.
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Special Processing:
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Lab Staff: Centrifuge specimen, remove serum/plasma aliquot into a plastic sample cup. Store at refrigerated temperatures.
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Patient Preparation:
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None
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Sample Rejection:
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Mislabeled or unlabeled specimen
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Interpretive
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Reference Range:
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Therapeutic Concentration:
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10 - 20 ug/mL
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Critical Values:
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Toxic concentration:
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>25 ug/mL
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Limitations:
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N/A
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Methodology:
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Particle-Enhanced Turbidimetric Inhibition Immunoassay
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References:
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Jacobs and DeMott Laboratory Test Handbook (2001) Lexi-comp, Inc, Hudson, OH, 5th ed
Theo Flex reagent cartridge insert sheet (4/22/2008) Siemens Healthcare Diagnostics Inc, 717071.001-US, Rev J
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Updates:
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12/22/2011: Turnaround time updated, previously listed as 4 hours.
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