Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

THEOPHYLLINE LEVEL

General Information

Lab Order Codes:

THEO

Synonyms:

Aminophylline; Theodur; Slo-Bid

CPT Codes:

80198 - Theophylline

Test Includes:

Theophylline concentration reported in ug/mL.

Logistics

Test Indications:

Theophylline relaxes bronchial smooth muscles to relieve or prevent asthma. Caffeine is a minor metabolite and is often seen in neonates taking theophylline. Peak levels are achieved in 30–90 minutes depending on the compound and type of preparation. The biologic half-life ranges from 3.5 hours in young children to 8–9 hours in adults.

Lab Testing Sections:

Chemistry (all specimens analyzed on the Mpls Campus)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

2 hours

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Green top (Li Heparin) tube preferred
Alternate tube: Red top (plain, no gel) tube

Draw Volume:

0.6 mL blood

Processed Volume:

0.2 mL serum/plasma

Collection:

Routine venipuncture. Mix tubes containing anticoagulant by gentle inversion.

Special Processing:

Lab Staff: Centrifuge specimen, remove serum/plasma aliquot into a plastic sample cup. Store at refrigerated temperatures.

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimen

Interpretive

Reference Range:

Therapeutic Concentration:

10 - 20 ug/mL

Critical Values:

Toxic concentration:

>25 ug/mL

Limitations:

N/A

Methodology:

Particle-Enhanced Turbidimetric Inhibition Immunoassay (PETINIA)

References:

Jacobs and DeMott Laboratory Test Handbook (2001) Lexi-comp, Inc, Hudson, OH, 5th ed

Siemens Dimension Vista THEO Flex Insert, PIN 781071.00, 11/6/2013, Rev D

Updates:

12/22/2011: Turnaround time updated, previously listed as 4 hours.



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