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Lab Dept:
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Chemistry
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Test Name:
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RHEUMATOID FACTOR, QUANTITATIVE
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General Information
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Lab Order Codes:
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RA
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Synonyms:
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RF; RA, Rheumatoid Arthritis Factor
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CPT Codes:
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86431– Rheumatoid factor; quantitative
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Test Includes:
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Rheumatoid factor concentration reported in IU/mL.
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Logistics
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Test Indications:
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Rheumatoid factor quantitates autoantibodies directed against IgG immunoglobulins and are members of a class of proteins that become elevated in inflammatory states. RA is most sensitive for monitoring the level of inflammation associated with rheumatoid arthritis.
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Lab Testing Sections:
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Chemistry (all specimens analyzed on the Mpls campus)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1 – 4 days, test performed Tuesday, Wednesday and Friday
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Special Instructions:
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N/A
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Specimen
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Specimen Type:
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Blood
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Container:
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Red top (plain, no gel) tube
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Draw Volume:
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0.6 mL blood
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Processed Volume:
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0.2 mL serum
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Collection:
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Routine collection
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Special Processing:
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Lab Staff: Centrifuge specimen, remove serum aliquot into a plastic sample cup. Specimens can be stored refrigerated for 8 days or frozen for 3 months. Centrifuge turbid or particulate samples prior to analysis.
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Patient Preparation:
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None
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Sample Rejection:
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Mislabeled or unlabeled specimen, specimens other than serum, turbid samples that do not clear after centrifugation
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Interpretive
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Reference Range:
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<15 IU/mL
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Critical Values:
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N/A
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Limitations:
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N/A
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Methodology:
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Nephelometry
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References:
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Tietz, NW, Textbook of Clinical Chemistry (1986) WB Saunders Co., Philadelphia, PA 1986, pp 52-53 (techniques and procedures to minimize laboratory infections) and pp 478-497 (specimen collection and storage recommendations)
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N Latex RF Kit OPCE 03 / 05 Product insert sheet (April 2008) Dade Behring, Marburg, Germany
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