Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

TSH, SENSITIVE

General Information

Lab Order Codes:

TSH

Synonyms:

Thyroid Stimulating Hormone; Ultra sensitive TSH

CPT Codes:

84443 – Thyroid stimulating hormone (TSH)

Test Includes:

TSH concentration reported in uIU/mL.

Logistics

Test Indications:

TSH is synthesized and secreted by the anterior pituitary. TSH is responsible for stimulating cell reproduction and hypertrophy. Secondly, TSH stimulates the thyroid gland to synthesize and secrete T3 and T4. The measurement of circulating TSH is important in evaluating hyperthyroidism.

Lab Testing Sections:

Chemistry (all specimens tested on the St. Paul campus)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

1 – 3 days, test performed Monday – Friday.

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Red top (plain, no gel) tube

Draw Volume:

1.5 mL blood

Processed Volume:

0.5 mL serum

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen, remove serum aliquot into a plastic sample cup. Store at refrigerated temperatures for up to 5 days.

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimen; specimens other than serum; gross hemolysis

Interpretive

Reference Range:

Age:

Range:

≤7 days:

3.2 - 21.0 uIU/mL

≥8 days:

0.5 – 4.8 uIU/mL

Critical Values:

N/A

Limitations:

Heterophile antibodies may interfere with immunoassay testing.

Methodology:

3rd Generation Competitive Chemiluminescent Immunoassay

References:

Siemens Immulite 2000 Third Generation TSH Product Insert (08/13/2008) Siemens Healthcare Diagnostics

DPC End User Procedure Manual Disk #0408111 (2005)

National Committee for Clinical Laboratory Standards (NCCLS) (2002) Clinical Laboratory Technical Procedure Manuals; Approved Guideline-Fourth Edition GP2-A4

Burtis CA, Ashwood ER, editors (1994) Tietz Textbook of Clinical Chemistry. 2nd ed. Philadelphia: W.B. Saunders

Biorad Immunoassay Plus Control Product Insert

Updates:

8/29/2005: Methold previously listed as Two Site Sandwich Immunoassay Direct Chemiluminescence standardized to WHO 3rd IRP reference material.
10/1/2008: Name change to include Sensitive.



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