Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

PROLACTIN

General Information

Lab Order Codes:

PROL

Synonyms:

N/A

CPT Codes:

84146 - Prolactin

Test Includes:

Prolactin concentration reported in ng/mL.

Logistics

Test Indications:

Useful for detecting prolactin-secreting pituitary tumors; aiding in the evaluation of hypothalmic disease, hypopituitarism, etc. Prolactin initiates and maintains lactation in females and suppresses gonadal function in both sexes.

Lab Testing Sections:

Chemistry

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

1 day

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Preferred: Green top (Li Hep) tube
Alternate: Red top (plain, no gel) tube

Draw Volume:

1.5 mL (Minimum: 0.6 mL) blood

Processed Volume:

0.5 mL (Minimum: 0.2 mL) plasma/serum

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen, remove plasma/serum aliquot into a plastic sample cup. Store at 2-8 degrees Centigrade for up to 7 days.

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimen

Interpretive

Reference Range:

Age:

Range:

Male:

1 - 7 days:

30 - 495 ng/mL

1 - 6 weeks:

29 - 145 ng/mL

6 - 8 weeks:

11 - 23 ng/mL

>2 months:

3 - 18 ng/mL

Female:

1 - 7 days:

30 - 495 ng/mL

1 - 6 weeks:

29 - 145 ng/mL

6 - 8 weeks:

11 - 23 ng/mL

>2 months:

3 - 24 ng/mL

Critical Values:

N/A

Limitations:

Heterophile antibodies may interfere with immunoassay testing.

Methodology:

Homogeneous Sandwich Chemiluminescent Immunoassay

References:

Siemens Dimension Vista Prolactin Directions For Use (7/12/2010) Siemens Healthcare Diagnostics

National Committee for Clinical Laboratory Standards (NCCLS) (2002) Clinical Laboratory Technical Procedure Manuals; Approved Guideline-Fourth Edition GP2-A4

Burtis CA, Ashwood ER, editors (2006) Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 4th ed. St Louis MO:Elsevier Saunders

Biorad Immunoassay Plus Control Product Insert

Updates:

7/22/2014: Method update, previously listed as Competitive Chemiluminescent Assay.



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