Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

AST

General Information

Lab Order Codes:

AST

Synonyms:

Aspartate Aminotransferase; SGOT; Serum Glutamic Oxaloacetic Transaminase

CPT Codes:

84450 - Transferase; aspartate amino (AST) (SGOT)

Test Includes:

Aspartate aminotransferase concentration reported in U/L.

Logistics

Test Indications:

The aminotransferases constitute a group of enzymes that catalyze the interconversion of amino acids and 2-oxo-acids by transfer of amino acids. AST and ALT are the two enzymes of greatest clinical significance. Elevated AST levels are found in hepatic disease, myocardial damage, pulmonary emboli, muscle injuries, muscular dystrophy, hemolytic disease, acute pancreatitis, or gangrene.

Lab Testing Sections:

Chemistry

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

4 hours

Special Instructions:

N/A

Specimen

Specimen Type:

Whole blood

Container:

Preferred: Green top (Li Heparin) tube
Alternate: Red top (plain, no gel) tube

Draw Volume:

0.6 mL blood

Processed Volume:

0.2 mL plasma/serum

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen, remove serum/plasma aliquot into plastic sample cup. Analyze sample immediately or store at refrigerated temperatures.

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimen; gross hemolysis

Interpretive

Reference Range:

Age:

Male Range (U/L):

Female Range (U/L):

0 – 2 months:

21 - 111 U/L

21 – 111 U/L

2 months – 2 years:

20 – 96 U/L

20 – 96 U/L

2 – 8 years:

23 – 75 U/L

23 – 75 U/L

8 – 16 years:

23 – 60 U/L

23 – 60 U/L

16 – 17 years:

23 – 45 U/L

23 – 45 U/L

>17 years:

27 – 47 U/L

22 – 37 U/L

Critical Values:

N/A

Limitations:

Hemolysis of the sample falsely increases the AST concentration.

Methodology:

Enzymatic, 37C

References:

AST Flex™ reagent cartridge insert sheet Siemens Healthcare Diagnostics Inc. 2008-02-12 F 717041.002 - US

Clinical Significance, Dade Behring Inc., Glasgow Business Community, Mailbox 531, P.O. Box 6101, Newark, Delaware 19714

Jacobs & DeMott Laboratory Test Handbook (2001) Lexi-Comp, Inc, Hudson, OH, 5th Edition

Biorad Liquichek Unassayed Chemistry Control Product Insert, Bio-Rad Laboratories, Irvine, CA 92618

Updates:

2/17/2005: Critical value previously listed >500 U/L.



  Lab Test Directory
    Chemistry
    Coagulation
    Flow/Immunology
    Hematology
    Microbiology/ Virology
    Other Fluids
    Pathology
    Serology
    Transfusion Services
    Urine/Stool

  Search Lab Test Directory
    List All Documents

  Lab Staff

  E-mail Lab Services