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Lab Dept:
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Chemistry
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Test Name:
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CARBOXY HEMOGLOBIN
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General Information
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Lab Order Codes:
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COHB
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Synonyms:
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Carboxy Hgb; Carbon Monoxide
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CPT Codes:
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82375 – Carbon monoxide (carboxyhemoglobin); quantitative
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Test Includes:
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Carboxyhemoglobin concentration reported as a % of total hemoglobin.
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Logistics
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Test Indications:
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Carbon monoxide has a much greater binding affinity for hemoglobin than does oxygen. Carboxyhemoglobin is a hemoglobin-carbon monoxide complex. Carbon monoxide is normally generated in small quantities from the catabolism of heme. Common exogenous sources include cigarette smoke, automobile exhaust, and poorly ventilated home heating units.
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Lab Testing Sections:
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Chemistry
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1 hour
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Special Instructions:
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Capillary tube samples will not be accepted. See Collection.
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Specimen
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Specimen Type:
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Whole blood
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Container:
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Sims Portex® syringe (PB151) or Smooth-E syringe (956-463) or Green- (Li Heparin) top tube
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Draw Volume:
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Preferred: 0.4 mL in Sims or Smooth-E syringe
Alternate: Completely filled green (lithium heparin) top tube, 2.7 mL of blood in a 3.0 mL tube.
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Processed Volume:
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0.2 mL whole blood
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Collection:
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Routine venipuncture. Do not expose specimen to air. Immediately remove all air from blood gas syringe, remove needle, cap tightly, and mix. Keep syringe/tube stoppered to avoid exposure of specimen to atmosphere. Forward promptly at ambient temperature only.
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Special Processing:
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Lab Staff: Deliver carboxyhemoglobin specimen to the blood gas workstation for testing. Specimens should be analyzed within one hour of collection.
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Patient Preparation:
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None
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Sample Rejection:
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Mislabeled or unlabeled specimen, samples containing air, capillary tubes, clotted specimens
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Interpretive
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Reference Range:
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0.0 – 1.5%
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Critical Values:
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N/A
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Limitations:
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N/A
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Methodology:
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Oximetry
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References:
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Tietz (1999) Textbook of Clinical Chemistry, 3rd edition, Philadelphia, WB Saunders Co, pp 918, 1662
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ABL 700 Series Operator Manual (November 2003) Edition D, Code number: 989-432
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ABL 700 Series Reference Manual (November 2003) Edition D, Code number: 989-312
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