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Lab Dept:
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Chemistry
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Test Name:
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DRUGS OF ABUSE SCREEN, URINE
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General Information
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Lab Order Codes:
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ABUS
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Synonyms:
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Urine drug screen
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CPT Codes:
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G0431 – Drug screen, qualitative; multiple drug classes by high complexity test method (e.g., immunoassay, enzyme assay), per patient encounter
Confirmations may be added at the request of the provider at an additional charge.
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Test Includes:
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Major metabolites of drugs of abuse (phencyclidine, benzodiazepines, cocaine metabolite, amphetamines, tetrahydrocannabinol, opiates, barbiturates) in urine. This test no longer includes TCA (Tricyclic Antidepressants).
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Logistics
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Test Indications:
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Useful for the qualitative determination of the presence of the major metabolites of drugs of abuse in urine.
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Lab Testing Sections:
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Chemistry
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1 hour or STAT (30 minutes)
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Special Instructions:
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Confirmatory testing, for positive screening results requires a separate order. Use Add Order in HIS (Hospital Information System) orders to request the specific confirmatory test.
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Specimen
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Specimen Type:
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Urine
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Container:
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Urine Cup
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Draw Volume:
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10 mL (Pediatric Minimum: 4 mL, Absolute Minimum: 1 mL) urine
Note: Collection of the Absolute Minimum volume does not permit confirmatory or repeat testing.
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Processed Volume:
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Same as Draw Volume
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Collection:
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Random urine
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Special Processing:
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Lab Staff: No preservative. Refrigerate specimen after collection. Centrifuge specimens containing particulates.
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Patient Preparation:
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None
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Sample Rejection:
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Unlabeled or mislabeled specimen, adulterated specimen
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Interpretive
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Reference Range:
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Negative
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This test differentiates between positive and negative specimens at the designated cut-off concentrations.
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Drug Name:
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Cut-off concentration:
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Confirmatory Test:
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Phencyclidine:
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25 ng/mL
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PCCON
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Benzodiazepines:
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200 ng/mL
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BECON
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Amphetamines:
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1000 ng/mL
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AMCON
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Cocaine (Benzoylecgonine):
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300 ng/mL
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COCON
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Tetrahydrocannabinol:
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50 ng/mL
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THCON
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Opiates (Morphine):
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300 ng/mL
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OPCON
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Barbiturates:
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200 ng/mL
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BACON
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Critical Values:
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Call any positive results
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Limitations:
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This test is a qualitative screening test. Confirm positive results by another method, such as GC/HPLC if indicated.
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Methodology:
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Syva® Emit II Immunoassay
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References:
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Jacobs and DeMott (2001) Laboratory Test Handbook, 5th edition, Lexi-Comp, Inc., Hudson, OH, p 788
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Dade Behring Dimension Flex Reagent Cartridge Inserts, Newark, DE, 19714 (See below for individual analyte)
AMPH Flex® reagent cartridge insert sheet PN 717091, 111 Issue Date 2004-2007, Rev B
BARB Flex® reagent cartridge insert sheet PN 717096, 101 Issue Date 2002/20 Rev E
BENZ Flex® reagent cartridge insert sheet PN 797097, 101 Issue Date 2002/06 Rev D
COC Flex® reagent cartridge insert sheet PN 707092, 101 Issue Date 2004-07 Rev E
OPI Flex® reagent cartridge insert sheet PN 717093, 101 Issue Date 2002-06 Rev D
PCP Flex® reagent cartridge insert sheet PN 717094, 102 Issue Date 2002-04 Rev D
THC Flex® reagent cartridge insert sheet PN 717095, 101 Issue Date 2003/02 Rev E
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Updates:
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4/27/2006: TCA (Tricyclic Antidepressants) are no longer part of this assay.
3/30/2009: Revised volume to include Pediatric Minimum.
5/11/2010: CPT update, previously reported as 80101.
2/8/2011: CPT update, quantity changed
1/3/2012: Test no longer includes TCA.
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