Useful for second-order testing for autoimmune thyroid disease, including:
Differential diagnosis of etiology of thyrotoxicosis in patients with ambiguous clinical signs and/or contraindicated (e.g., pregnant or breast-feeding) or indeterminate thyroid radioisotope scans.
Diagnosis of clinically suspected Graves’ disease (e.g., extrathyroidal manifestations of Graves’ disease; endocrine expphthalmos, pretibial myxedema, thyroid acropachy) but normal thyroid function tests.
Determining the risk of neonatal thyrotoxicosis in a fetus of a pregnant female with active or past Graves’ disease.
Differential diagnosis of gestational thyrotoxicosis versus first trimester manifestation of recurrence of Graves’ disease.
Assessing the risk of Graves’ disease relapse after antithyroid drug treatment.
A combination of TSI and Thyrotropin Receptor Antibody is useful as an adjunct in the diagnosis of unusual cases of hypothyroidism (e.g., Hahitoxicosis)