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Lab Dept:
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Chemistry
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Test Name:
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PREGNENOLONE, SERUM
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General Information
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Lab Order Codes:
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PRGNL
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Synonyms:
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N/A
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CPT Codes:
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84140 - Pregnenolone
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Test Includes:
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Pregnenolone concentration reported as ng/dL.
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Logistics
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Test Indications:
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Pregnenolone is the precursor (building-block) for all other steroid hormones. It is converted directly into DHEA and/or progesterone. DHEA converts to testosterone and estrogens; progesterone converts to estrogens, cortisol, and aldosterone.
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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Esoterix (Test#: 500258)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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5 – 8 days, performed Monday – Thursday, Saturday
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Special Instructions:
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N/A
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Specimen
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Specimen Type:
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Blood
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Container:
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Red top tube
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Draw Volume:
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6 mL (Minimum: 1.5 mL) blood
Note: Minimum volume does not allow for repeat analysis.
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Processed Volume:
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2 mL (Minimim: 0.5 mL) serum
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Centrifuge specimen and remove serum aliquot into a screw-capped plastic vial. Store and ship at frozen temperatures. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Specimens other than serum; mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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Age
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Range (ng/dL)
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Premature (26-28 wks) Day 4
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260 - 2104
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Premature (34-36 wks) Day 4
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203 - 1024
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Neonates (1 – 7 days)
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150 - 2000
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Prepubertal
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20 - 140
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Pubertal and Adults
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<20 - 150
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Levels decrease after birth and are within the prepubertal range of 20 – 140 by 3 months.
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Critical Values:
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N/A
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Limitations:
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N/A
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Methodology:
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HPLC – Tandem Mass Spectrometry
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References:
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Esoterix Laboratory Services April 2012
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