Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

PREGNENOLONE, SERUM

General Information

Lab Order Codes:

PRGNL

Synonyms:

N/A

CPT Codes:

84140 - Pregnenolone

Test Includes:

Pregnenolone concentration reported as ng/dL.

Logistics

Test Indications:

Pregnenolone is the precursor (building-block) for all other steroid hormones. It is converted directly into DHEA and/or progesterone. DHEA converts to testosterone and estrogens; progesterone converts to estrogens, cortisol, and aldosterone.

Lab Testing Sections:

Chemistry - Sendouts

Referred to:

Esoterix (ESL Test: 500258)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

5 – 8 days, performed Monday – Thursday, Saturday

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Red top tube

Draw Volume:

6 mL (Minimum: 1.5 mL) blood
Note: Minimum volume does not allow for repeat analysis.

Processed Volume:

2 mL (Minimim: 0.5 mL) serum

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen and remove serum aliquot into a screw-capped plastic vial. Store and ship at frozen temperatures. Forward promptly.

Patient Preparation:

None

Sample Rejection:

Specimens other than serum; mislabeled or unlabeled specimens

Interpretive

Reference Range:

Age

Range (ng/dL)

Premature (26-28 wks) Day 4

260 - 2104

Premature (34-36 wks) Day 4

203 - 1024

Neonates (1 – 7 days)

150 - 2000

Prepubertal

20 - 140

Pubertal and Adults

<20 - 150

Levels decrease after birth and are within the prepubertal range of 20 – 140 by 3 months.

Critical Values:

N/A

Limitations:

N/A

Methodology:

HPLC – Tandem Mass Spectrometry

References:

Esoterix Laboratory Services April 2012



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