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Lab Dept:
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Chemistry
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Test Name:
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TRYPTASE, SERUM
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General Information
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Lab Order Codes:
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TRYPT
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Synonyms:
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Mast Cell Tryptase; Soft-TRYPT
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CPT Codes:
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83520 – Immumoassay for analyte other than infectious agent Ab or infectious agent Ag; Quantitative NOS.
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Test Includes:
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Tryptase concentration measured ng/mL.
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Logistics
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Test Indications:
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Useful for assessing mast cell activation, which may occur as a result of anaphylaxis, or allergen challenge, or in patients with systemic mastocytosis or mast cell activation syndrome.
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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Mayo Medical Laboratories (Test# 81608)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1-3 days, test performed Monday – Friday
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Special Instructions:
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N/A
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Specimen
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Specimen Type:
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Blood
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Container:
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Red top or serum gel tube
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Draw Volume:
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1.5 mL (Minimum: 0.6 mL) blood
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Processed Volume:
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0.5 mL (Minimum: 0.2 mL) serum
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Collection:
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Routine venipuncture, invert gently to mix.
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Special Processing:
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Lab Staff: Centrifuge specimen, remove serum aliquot into a screw-capped round bottom plastic vial. Store and ship at frozen temperatures. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Specimen other serum; mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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<11.5 ng/mL
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Critical Values:
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N/A
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Limitations:
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Tryptase may be undetectable or not elevated in some patients with acute mast cell activation if specimens are drawn >12 hours after an anaphylactic episode.
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Methodology:
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Fluorescence Enzyme Immunoassay (FEIA)
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References:
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Mayo Medical Laboratories September 2012
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