Clinics and Departments

Laboratory Services

Lab Dept:

Chemistry

Test Name:

TRYPTASE, SERUM

General Information

Lab Order Codes:

TRYPT

Synonyms:

Mast Cell Tryptase; Soft-TRYPT

CPT Codes:

83520 – Immumoassay for analyte other than infectious agent Ab or infectious agent Ag; Quantitative NOS.

Test Includes:

Tryptase concentration measured ng/mL.

Logistics

Test Indications:

Useful for assessing mast cell activation, which may occur as a result of anaphylaxis, or allergen challenge, or in patients with systemic mastocytosis or mast cell activation syndrome.

Lab Testing Sections:

Chemistry - Sendouts

Referred to:

Mayo Medical Laboratories (Test: TRYPT/81608)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

1-3 days, test performed Monday – Friday

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Red top or serum gel tube

Draw Volume:

1.5 mL (Minimum: 0.6 mL) blood

Processed Volume:

0.5 mL (Minimum: 0.2 mL) serum

Collection:

Routine venipuncture, invert gently to mix.

Special Processing:

Lab Staff: Centrifuge specimen, remove serum aliquot into a screw-capped round bottom plastic vial. Store and ship at frozen temperatures. Forward promptly.

Patient Preparation:

None

Sample Rejection:

Specimen other serum; mislabeled or unlabeled specimens

Interpretive

Reference Range:

<11.5 ng/mL

Critical Values:

N/A

Limitations:

Tryptase may be undetectable or not elevated in some patients with acute mast cell activation if specimens are drawn >12 hours after an anaphylactic episode.

Methodology:

Fluorescence Enzyme Immunoassay (FEIA)

References:

Mayo Medical Laboratories September 2012



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