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Lab Dept:

Chemistry

Test Name:

PARATHYROID HORMONE-RELATED PEPTIDE

General Information

Lab Order Codes:

PHRP

Synonyms:

Parathyroid Related Protein

CPT Codes:

82397 – Chemiluminescent assay

Test Includes:

PTH-related peptide reported in pmol/L.

Logistics

Test Indications:

Useful for diagnostic work-up of patients with suspected hypercalcemia of malignancy; diagnostic work-up of patients with hypercalcemia of unknown origin.

Lab Testing Sections:

Chemistry – Sendouts

Referred to:

Mayo Medical Laboratories (Test: PTHRP/81774)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

3 - 5 days

Special Instructions:

An ice-cooled, lavender top tube MUST be used.

Specimen

Specimen Type:

Blood

Container:

Ice-cooled, Lavender top (EDTA) tube

Draw Volume:

2.5 mL (Minimum: 1 mL) blood

Processed Volume:

0.7 mL (Minimum: 0.25 mL) serum

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge immediately in a refrigerated centrifuge or in chilled centrifuge cups, remove plasma aliquot into a screw-capped round bottom plastic vial. Store and ship at frozen temperatures. Forward promptly.

Patient Preparation:

None

Sample Rejection:

Specimens other than EDTA plasma; mislabeled or unlabeled specimens

Interpretive

Reference Range:

All ages: <2.0 pgmol/L

Critical Values:

N/A

Limitations:

Like all immunometric assays, PTHrP assays are susceptible to falsely low results at extremely high analyte concentrations (“hooking”) and to rare false positive results due to heterophile interference.

Methodology:

Immunochemiluminometric Assay (ICMA)

References:

Mayo Medical Laboratories March 2013



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