Lab Dept:

Coagulation

Test Name:

HEPARIN COFACTOR II CHROMOGENIC

General Information

Lab Order Codes:

HCOF

Synonyms:

Heparin Cofactor; Heparin Cofactor II, Blood

CPT Codes:

85130 - Chromogenic substrate assay

Test Includes:

Heparin cofactor activity reported as a %.

Logistics

Test Indications:

Useful in the evaluation of familial thrombosis, deep vein thrombosis, myocardial infarction, and in risk of post-operative thrombosis.

Lab Testing Sections:

Coagulation - Sendouts

Referred to:

Fairview University Medical Center

Phone Numbers:

Minneapolis:

Saint Paul:

612-813-6280

651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

2 - 7 days, test performed at reference lab once a week

Special Instructions:

Must arrive at reference lab with in 24 hours. Deliver immediately to the laboratory.

Specimen

Specimen Type:

Whole Blood

Container:

Light Blue top (Buffered Na Citrate 3.2%) tube

Draw Volume:

4.5 mL blood in a 5 mL tube (Minimum: 2.7 mL in a 3 mL tube)

Processed Volume:

Specimen will be processed by reference lab facility.

Collection:

A clean venipuncture is essential.Do Not use the first 2 mL’s of blood collected.

Patient’s with hematocrit levels >55% must have a special tube made to adjust for the hematocrit; contact laboratory for special tube.

Mix thoroughly by gentle inversion.

Special Processing:

Lab Staff: Do Not centrifuge. Send in original Vacutainer® tube.

Patient Preparation:

None

Sample Rejection:

Improper tube, Clotted sample, Underfilled tubes, Overfilled tubes, Specimen over 24 hours old, Mislabeled or unlabeled specimens

Interpretive

Reference Range:

≥1 year: 65 - 135%

Critical Values:

N/A

Limitations:

N/A

Methodology:

Chromogenic Activity Assay

References:

Fairview University Medical Center Laboratory Web Page http://labguide.fairview.org/diagnostic.asp

Harmening DH (1997) Clinical Hematology and Fundamentals of Hemostasis

Updates:

5/25/2010: Tubing patient specimens is no longer prohibited.