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Lab Dept:
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Coagulation
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Test Name:
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FACTOR 13 ANTIGEN SUBUNIT A
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General Information
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Lab Order Codes:
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F13SU
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Synonyms:
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Factor 13 Immunologic Assay; Factor 13A
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CPT Codes:
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85290 – Factor 13 (fibrin stabilizing)
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Test Includes:
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Antigen level for subunit A reported as a %.
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Logistics
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Test Indications:
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Defective wound healing, delayed bleeding episodes and habitual abortions are symptoms of Factor 13 deficiency. The most common sites of hemorrhage are umbilical cord stump (80%), which is often spontaneous or after mild trauma.
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Lab Testing Section:
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Coagulation - Sendouts
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Referred to:
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Fairview University Medical Center (Test# 13AGN)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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4 hours if received on Monday – Friday: 0700-1730 or Saturday: 1000-1330.
For urgent testing after hours, contact Children’s laboratory and they will call Fairview’s tech on call. Results reported within 10 days.
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Special Instructions:
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Patient should not be receiving heparin. If so, this should be noted on the request form. Heparin can affect certain coagulation factors or assay, preclude their performance, or cause spurious results.
Indicate when the specimen is drawn from a line or a heparin lock. Deliver immediately to the laboratory.
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Specimen
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Specimen Type:
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Whole blood
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Container:
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Light Blue top (Buffered Na Citrate 3.2%) tube
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Draw Volume:
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2.7 mL blood in a 3 mL tube (Minimum: 1.8 mL in a 2 mL tube)
Please respect fill line on tube.
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Processed Volume:
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Specimen will be processed by the reference lab facility.
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Collection:
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Routine venipuncture. Do Not use the first 2 mL’s of blood collected.
If the patient’s hematocrit is >55%, contact laboratory to obtain a special tube.
Mix thoroughly by gentle inversion.
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Special Processing:
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Lab Staff: Do Not centrifuge. Ship at room temperature. Must arrive within 24 hours of collection. Forward promptly.
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Patient Preparation:
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If the patient has a coagulation abnormality, apply direct pressure to the puncture site for 10 minutes; apply pressure bandage. Instruct the patient to leave the bandage on for 12 hours.
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Sample Rejection:
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Improper tube; clotted samples; underfilled tubes; overfilled tubes; mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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Age:
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Reference range (%):
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0 – 4 days
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53 – 105%
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5 – 29 days
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69 – 119%
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30 – 89 days
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66 – 120%
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90 – 179 days
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70 – 138%
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180 – 364 days
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75 – 133%
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1 year and older
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60 – 130%
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Critical Values:
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N/A
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Limitations:
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N/A
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Methodology:
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Laurell Rocket immunoelectrophoresis
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References:
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Fairview University Diagnostic Laboratories April 2011
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Updates:
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5/19/2004: As of February 2004, Fairview no longer performs Subunit S as part of this test. References to Subunit S have been removed. Draw volume changed from 4.5 mL to 2.7 mL blood.
7/15/2004: Reference range changed from 66-150% to 60-130% for patients 1 year and older.
5/25/2010: Tubing patient specimens is no longer prohibited.
3/31/2011: CPT update and reference range update.
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