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Lab Dept:
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Coagulation
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Test Name:
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FACTOR V (FAIRVIEW UNIVERSITY)
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General Information
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Lab Order Codes:
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F5U
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Synonyms:
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Labile Factor; Proaccelerin; Factor V Assay
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CPT Codes:
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85220 – Clotting; factor V (AcG or proaccelerin), labile factor
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Test Includes:
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Factor V activity reported as a %.
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Logistics
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Test Indications
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Useful for the detection of a single factor congenital heterozygous or homozygous deficiency or in conjunction with Factor VIII, liver disease.
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Lab Testing Section:
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Sendouts - Coagulation
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Referred to:
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Fairview University Medical Center (Test# F5)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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4 hours if received on Monday – Friday: 0700-1730 or Saturday: 1000-1300. 1 day if received outside of these regular working hours. Stats are done within 1 hour of receipt in the laboratory.
For urgent testing after hours, contact Children’s laboratory and they will call Fairview’s tech on call.
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Special Instructions:
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Patient should not be receiving heparin. If so, this should be noted on the request form. Heparin therapy can affect certain coagulation factors or assays, preclude their performance, or cause spurious results.
Indicate when specimen is drawn from a line or a heparin lock. Deliver immediately to the laboratory.
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Specimen
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Specimen Type:
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Whole blood
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Container:
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Light Blue-top (Buffered Na Citrate 3.2%) tube
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Draw Volume:
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2.7 mL blood in a 3 mL tube
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Processed Volume:
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Specimen will be processed at the reference lab facility.
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Collection:
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Routine venipuncture. Do Not use the first 2 mL’s of blood collected.
Patients with Hematocrit levels of >55% must have a special tube made to adjust for the hematocrit, contact laboratory for special tube.
Mix thoroughly by gentle inversion.
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Special Processing:
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Lab Staff: Do Not centrifuge. Send to reference lab in original Vacutainer® at room temperature. Must arrive at reference lab within 24 hours of collection.
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Patient Preparation:
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Avoid heparin therapy for 2 days prior to test.
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Sample Rejection:
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Improper tube; clotted samples; underfilled tubes; overfilled tubes; mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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Age:
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Range(%):
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<1 day:
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91 – 190%
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1 – 4 days:
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54 – 90%
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5 – 29 days:
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70 – 120%
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30 – 89 days:
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80 – 116%
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90 – 179 days:
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69 – 111%
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180 – 364 days:
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73 – 109%
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≥1 year:
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60 - 140%
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Critical Values:
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N/A
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Limitations:
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Interpretation of results may be limited if patient is receiving anticoagulant therapy or if test is done more than 2 hours after collection.
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Methodology:
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Thromboplastin clotting time correction of Factor 5 deficient plasma. Patient dilutions are compared to a known set of standard dilutions and a percentage is determined.
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References:
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Fairview University Web Page July 2012
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Harmening DH (1997) Clinical Hematology and Fundamentals of Hemostasis
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Updates:
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5/27/2004: Reference ranges changed from 70-130% to 60-140%. Draw volume reduced from 4.5 mL in a 5 mL tube to 2.7 mL in a 3 mL tube.
10/7/2005: Reference ranges added for 0-5 days, previously only listed for greater than or equal to 1 year.
5/25/2010: Tubing patient specimens is no longer prohibited.
6/15/2011: Reference range update.
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