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Lab Dept:
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Coagulation
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Test Name:
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ALPHA-2 ANTIPLASMIN CHROMOGENIC
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General Information
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Lab Order Codes:
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A2AC
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Synonyms:
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Alpha 2 Antiplasmin Activity; Antiplamin Functional Assay
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CPT Codes:
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85410 – Alpha-2 antiplasmin
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Test Includes:
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Antiplasmin activity level reported as a %.
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Logistics
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Test Indications:
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Alpha-2 Antiplasmin is a specific inhibitor of Plasmin. A deficiency may result in a bleeding tendency. Homozygous deficiency may cause severe bleeding.
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Lab Testing Sections:
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Coagulation - Sendouts
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Referred to:
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Fairview University Medical Center (Test# APCH)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours. Test is performed as needed.
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Turnaround Time:
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Within 7 days
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Special Instructions:
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Indicate when specimen is drawn from a line or a heparin lock. Deliver immediately to the laboratory.
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Specimen
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Specimen Type:
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Whole blood
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Container:
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Light Blue top (Buffered Na Citrate 3.2%) tube
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Draw Volume:
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2.7 mL blood in a 3 mL tube (Minimum: 1.8 mL in a 2 mL tube).
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Processed Volume:
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Specimen will be processed by the reference lab facility.
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Collection:
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Do Not use the first 2 mL’s of blood collected.
Patients with hematocrit levels of >55% must have a special tube made to adjust for the hematocrit, contact laboratory for special tube.
Fill tube completely. Mix thoroughly by gentle inversion.
If the patient has a coagulation abnormality, apply direct pressure to the puncture site for 10 minutes; apply a pressure dressing. Instruct the patient to leave the bandage on for 12 hours.
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Special Processing:
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Lab Staff: Do Not process. Send to reference lab in original Vacutainer® at room temperature within 24 hours.
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Patient Preparation:
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None
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Sample Rejection:
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Improper tube, Clotted samples, Underfilled tubes, Overfilled tubes, Mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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≥1 Year: 75 – 126%
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Critical Values:
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N/A
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Limitations:
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N/A
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Methodology:
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Chromogenic (synthetic substrate) activity assay
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References:
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Fairview University Web Page July 2012
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Harmening DH (1997) Clinical Hematology and Fundamentals of Hemostasis
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Updates:
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5/25/2010: Tubing patient specimens is no longer prohibited.
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