Clinics and Departments

Laboratory Services

Lab Dept:

Hematology

Test Name:

EOSINOPHILS, TOTAL COUNT

General Information

Lab Order Codes:

EOCT

Synonyms:

Total Eos; Eo Count; Absolute Number of Eosinophils

CPT Codes:

85021 – Hemogram, automated
85008 – Manual blood smear examination with differential parameters

Test Includes:

The total eosinophil count in blood reported in Eos/mm3

Logistics

Test Indications:

Useful in determining presence of eosinopenia or eosinophilia in the peripheral blood which can be present in a variety of conditions: adrenal response to ACTH, allergic reactions, parasitic infections, skin disorders, hypereosinophilic syndromes, neoplastic diseases and other miscellaneous disease states

Lab Testing Sections:

Hematology

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

4 hours

Special Instructions:

Do Not collect specimen while lipids are being infused.

Specimen

Specimen Type:

Whole blood

Container:

Lavender top tube (EDTA) or Lavender Microtainer®

Draw Volume:

2 mL blood in a Lavender tube OR 0.5 mL blood in a Microtainer®

Processed Volume:

Same as Draw Volume

Collection:

Fill to mark on tube or Microtainer®. Mix well by gentle inversion.

Special Processing:

Lab Staff: Do Not centrifuge. Process as whole blood.

Patient Preparation:

None

Sample Rejection:

Improper tube; clotted sample; underfilled tube; mislabeled or unlabeled specimen

Interpretive

Reference Range:

50 – 250 Eos/mm3

Eosinopenia: <50 Eos/mm3

Eosinophilia: >450 Eos/mm3

A definite diurnal variation occurs with a mid-morning nadir, approximately 20% less than the 0800 level; a maximal nocturnal peak, approximately 30% greater than the 0800 level. This diurnal variation is not observed in patients with adrenal insufficiency.

Critical Values:

N/A

Limitations:

Estimates of eosinophil numbers based on differential counts and stained blood smears are subject to error because the natural stickiness or adherence of eosinophils prevents even distribution.

Methodology:

Automated cell counter with automated or manual differential.

References:

Davidson, Henry, Todd-Sanford (1979) Clinical Diagnosis by Laboratory Methods, 15th ed

Harmening DH (1997) Clinical Hematology and Fundamentals of Hemostasis, 3rd ed

Oski and Nathan (1998) Hematology of Infancy and Childhood, 5th ed



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