Clinics and Departments

Laboratory Services

Lab Dept:

Hematology

Test Name:

HEINZ BODY STAIN

General Information

Lab Order Codes:

HB

Synonyms:

Stain for Heinz Bodies; Stain for unstable hemoglobin; G-6-PDH, Qualitative

CPT Codes:

85441 – Heinz bodies; direct

Test Includes:

Staining of red cells for aggregates of denatured hemoglobin (Heinz bodies).

Logistics

Test Indications:

Evaluate hemolytic anemias with RBC enzyme deficiencies (eg, GG PD deficiency), hemoglobin, congenital Heinz Body hemolytic anemia (CHBHA). Perform when many “bite cells” are seen on routine peripheral smears.

Lab Testing Sections:

Hematology - Sendout

Referred to:

Fairview University Medical Center (Test# HEINZ)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

1 - 3 days; performed Monday - Friday

Special Instructions:

Specimens drawn before transfusion are preferred. For best results, specimen should arrive at Fairview-University by 1400 Monday - Friday.

Specimen

Specimen Type:

Whole blood

Container:

Lavender top (EDTA) tube

Draw Volume:

3 mL (Minimum: 1 mL) blood

Processed Volume:

Same as Draw Volume

Collection:

Routine blood collection. Mix specimen thoroughly by gentle inversion.

Special Processing:

Lab Staff: Do Not centrifuge. Specimen should remain in original collection container. Store and ship at refrigerated temperatures. Forward promptly. Note: For best results, specimen should arrive at Fairview-University by 1400 Monday - Friday.

Patient Preparation:

None

Sample Rejection:

Improper tube; clotted tube; hemolyzed specimen; mislabeled or unlabeled specimens

Interpretive

Reference Range:

<1.0%
Less than 1% is usually considered normal in non-splenectomized patients.

Critical Values:

Above 1%

Limitations:

N/A

Methodology:

Supravital staining with basic dyes

Contraindications:

Recent transfusion

References:

Schwab (1969) An Improved Stain for Heinz Bodies, AJCP 51:5, 673-5

Fairview Medical Center Diagnostic Laboratory Web Page http://labguide.fairview.org/showTest.asp?testid=976 January 2012



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