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Lab Dept:
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Hematology
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Test Name:
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HEINZ BODY STAIN
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General Information
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Lab Order Codes:
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HB
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Synonyms:
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Stain for Heinz Bodies; Stain for unstable hemoglobin; G-6-PDH, Qualitative
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CPT Codes:
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85441 – Heinz bodies; direct
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Test Includes:
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Staining of red cells for aggregates of denatured hemoglobin (Heinz bodies).
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Logistics
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Test Indications:
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Evaluate hemolytic anemias with RBC enzyme deficiencies (eg, GG PD deficiency), hemoglobin, congenital Heinz Body hemolytic anemia (CHBHA). Perform when many “bite cells” are seen on routine peripheral smears.
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Lab Testing Sections:
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Hematology - Sendout
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Referred to:
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Fairview University Medical Center (Test# HEINZ)
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Phone Numbers:
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MIN Lab: 612-813-6280
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STP Lab: 651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1 - 3 days; performed Monday - Friday
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Special Instructions:
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Specimens drawn before transfusion are preferred. For best results, specimen should arrive at Fairview-University by 1400 Monday - Friday.
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Specimen
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Specimen Type:
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Whole blood
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Container:
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Lavender top (EDTA) tube
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Draw Volume:
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3 mL (Minimum: 1 mL) blood
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Processed Volume:
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Same as Draw Volume
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Collection:
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Routine blood collection. Mix specimen thoroughly by gentle inversion.
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Special Processing:
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Lab Staff: Do Not centrifuge. Specimen should remain in original collection container. Store and ship at refrigerated temperatures. Forward promptly. Note: For best results, specimen should arrive at Fairview-University by 1400 Monday - Friday.
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Patient Preparation:
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None
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Sample Rejection:
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Improper tube; clotted tube; hemolyzed specimen; mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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<1.0%
Less than 1% is usually considered normal in non-splenectomized patients.
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Critical Values:
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Above 1%
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Limitations:
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N/A
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Methodology:
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Supravital staining with basic dyes
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Contraindications:
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Recent transfusion
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References:
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Schwab (1969) An Improved Stain for Heinz Bodies, AJCP 51:5, 673-5
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Fairview Medical Center Diagnostic Laboratory Web Page http://labguide.fairview.org/showTest.asp?testid=976 January 2012
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