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Lab Dept:
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Hematology
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Test Name:
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HEMOGLOBIN F, BLOOD
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General Information
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Lab Order Codes:
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HBF
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Synonyms:
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Hemoglobin F; Fetal Hemoglobin; APT test; Hemoglobin F, Alkalai Resistant
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CPT Codes:
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83021 – Hemoglobin fractionation and quantitation; chromatography
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Test Includes:
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The percent presence of hemoglobin F.
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Logistics
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Test Indications:
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Useful in quantitating the percent of fetal hemoglobin present to assist in the diagnosis of disorders with elevated levels of fetal hemoglobin.
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Lab Testing Sections:
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Hematology – Sendouts
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Referred to:
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Mayo Medical Laboratories (MML Test# HBF/8269)
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Phone Numbers:
Minneapolis:
Saint Paul:
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812-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1 – 3 days, test set up Monday - Saturday
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Special Instructions:
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N/A
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Specimen
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Specimen Type:
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Whole blood
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Container:
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Lavender top (EDTA) tube
Alternate: Yellow top (ACD) or Green top (Na Heparin) tubes
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Draw Volume:
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3 mL (Minimum: 1 mL) blood
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Processed Volume:
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Same as Draw Volume
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Do Not Centrifuge. Send specimen in original collection container. Store and ship at refrigerated temperatures. Do Not freeze. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Specimens other than whole blood; frozen specimens; anticoagulants other than EDTA or heparin; hemolyzed specimens; mislabeled specimens
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Interpretive
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Reference Range:
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Age:
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Range:
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0 – 30 days
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60 – 90%
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1 – 23 months
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Varies
Note: Adult values attained by 24 months.
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>24 months
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0 – 2%
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Critical Values:
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N/A
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Limitations:
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Hemoglobin F is elevated in newborns, reaching adult levels by 12 months. It is also commonly increased to as much as 5-10% in normal pregnancy.
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Methodology:
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HPLC (high-performance liquid chromatography)
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References:
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Mayo Medical Laboratories Web Page September 2012
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