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Lab Dept:
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Microbiology/Virology
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Test Name:
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STREP PNEUMONIAE ANTIGEN, URINE
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General Information
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Lab Order Codes:
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SPAU
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Synonyms:
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Pneumococcal Pneumonia; Pneumococcus
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CPT Codes:
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87899 – Infectious agent antigen detection by enzyme immunoassay with direct optical observation, not otherwise specified.
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Test Includes:
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Detection of Pneumococcal antigen.
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Logistics
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Lab Testing Sections:
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Microbiology - Sendouts
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Referred to:
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Mayo Medical Laboratories (MML Test#: 83150)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-5866
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651-220-6555
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1 – 3 days, performed Monday - Friday
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Special Instructions:
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Specimen site and date/time of collection are required for processing.
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Specimen
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Specimen Type:
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Urine
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Container:
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Sterile container
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Volume:
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2 mL
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Collection:
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Urine:
Males:
1. Clean glans with soap and water.
2. Rinse area with wet gauze pads.
3. While holding foreskin retracted, begin voiding.
4. After several mL have passed, collect a minimum of 2.0 mL without stopping flow of urine.
5. Maintain sterility and forward immediately to the Microbiology lab.
Females:
1. Thoroughly clean urethral area with soap and water.
2. Rinse area with wet gauze pads.
3. While holding labia apart, begin voiding.
4. After several mL have passed, collect a minimum of 2.0 mL without stopping flow of urine.
5. Maintain sterility and forward immediately to the Microbiology lab.
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Transport/Storage:
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Transport to the Microbiology Laboratory immediately at room temperature.
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Sample Rejection:
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Specimen with a transit time exceeding 4 hours after collection; specimen not submitted in appropriate transport container; improperly labeled specimen. If an unacceptable specimen is received, the physician or nursing station will be notified and another specimen will be requested before the specimen is discarded.
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Interpretive
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Reference Range:
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Negative
Interpretation: A positive result is indicative of pneumococcal pneumonia.
A negative result is presumptive for pneumococcal pneumonia, suggesting no current or recent pneumococcal infection. Infection due to Streptococcus pneumoniae cannot be ruled out since the antigen present in the specimen may be below the detection limit.
Pneumococcal pneumonia is best diagnosed by sputum culture.
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Limitations:
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A negative result does not exclude Streptococcus pneumoniae infection.
A diagnosis of Streptococcus pneumoniae must take into consideration all test results, culture results, and the clinical presentation of the patient.
Streptococcus pneumoniae vaccine may cause false-positive results, especially in patients who have received the vaccine within 5 days of having the test performed.
The performance of this assay in patients who have received antibiotics for >24 hours has not been established.
The accuracy of this assay has not been proven in small children.
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Methodology:
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Immunochromatographic Membrane Assay
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References:
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Mayo Medical Laboratories February 2010
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Updates:
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1/16/2012: CPT update, previously listed as 87450.
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