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Lab Dept:
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Anatomic Pathology
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Test Name:
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CHROMOSOMES, BONE MARROW
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General Information
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Lab Order Codes:
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CBM (Fairview University), CABM (ANW)
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Synonyms:
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Bone Marrow Chromosome
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CPT Codes:
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88237 - Tissue culture for neoplastic disorders; bone marrow, blood cells
88262-26 - Chromosome analysis; count 15-20 cells, 2 karyotypes, with banding (if appropriate)
88264 - Chromosome analysis; analyze 20-25 cells
88280 - Chromosome analysis; additional karyotypes, each study
88280-26 - Chromosome analysis; additional karyotypes, each study (if appropriate)
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Test Includes:
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Chromosome karyotype
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Logistics
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Test Indications:
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Useful for detecting malignant and premalignant hematologic disorders, residual disease, and as a preliminary test for bone marrow transplant.
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Lab Testing Section:
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Anatomic Pathology - Sendouts
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Referred to:
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Mpls. – Fairview-University Diagnostic Laboratories
St. Paul – Abbott-Northwestern Hospital Laboratories
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Phone Numbers:
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MIN Lab: 612-813-6711
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STP Lab: 651-220-6560
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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Results are reported within 2-21 days
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Special Instructions:
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Request form should include date and time of specimen collection, attending physician, diagnosis (or reason for referral), clinical status, information regarding medication or transfusions, and specimen type.
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Specimen
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Specimen Type:
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Bone Marrow aspirate or trephine biopsy
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Container:
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Bone marrow aspirate: Collect in sterile sodium heparin syringe.
Bone marrow biopsy: Collect in sterile specimen cup with tissue culture medium.
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Draw Volume:
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5 mL (Minimum: 3 mL) aspirate; 1 cm trephine biopsy
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Processed Volume:
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Same as Draw Volume
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Collection:
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If aspiration is impossible, a trephine biopsy should be obtained. Collect 5 mL of Na heparinized peripheral blood in addition to the bone marrow in all cases of newly diagnosed Acute Leukemia and Chronic Lymphocytic Leukemia.
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Special Processing:
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Store at room temperature. Do Not refrigerate of freeze. Ship at room temperature. Must arrive within 24 hours.
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Patient Preparation:
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Physician preference
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Sample Rejection:
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Clotted bone marrow
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Interpretive
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Reference Range:
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46, XX or 46, XY
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Methodology:
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Determined by laboratory director based on clinical information.
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References:
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Fairview-University Diagnostic Laboratory Web Page http://labguide.fairview.org/diagnostic.asp
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Abbott-Northwestern Cytogenetics Laboratory
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