Clinics and Departments

Laboratory Services

Lab Dept:

Anatomic Pathology

Test Name:

CHROMOSOMES, BONE MARROW

General Information

Lab Order Codes:

CBM (Fairview University), CABM (ANW)

Synonyms:

Bone Marrow Chromosome

CPT Codes:

88237 - Tissue culture for neoplastic disorders; bone marrow, blood cells
88262-26 - Chromosome analysis; count 15-20 cells, 2 karyotypes, with banding (if appropriate)
88264 - Chromosome analysis; analyze 20-25 cells
88280 - Chromosome analysis; additional karyotypes, each study
88280-26 - Chromosome analysis; additional karyotypes, each study (if appropriate)

Test Includes:

Chromosome karyotype

Logistics

Test Indications:

Useful for detecting malignant and premalignant hematologic disorders, residual disease, and as a preliminary test for bone marrow transplant.

Lab Testing Section:

Anatomic Pathology - Sendouts

Referred to:

Mpls. – Fairview-University Diagnostic Laboratories
St. Paul – Abbott-Northwestern Hospital Laboratories

Phone Numbers:

MIN Lab: 612-813-6711

STP Lab: 651-220-6560

Test Availability:

Daily, 24 hours

Turnaround Time:

Results are reported within 2-21 days

Special Instructions:

Request form should include date and time of specimen collection, attending physician, diagnosis (or reason for referral), clinical status, information regarding medication or transfusions, and specimen type.

Specimen

Specimen Type:

Bone Marrow aspirate or trephine biopsy

Container:

Bone marrow aspirate: Collect in sterile sodium heparin syringe.

Bone marrow biopsy: Collect in sterile specimen cup with tissue culture medium.

Draw Volume:

5 mL (Minimum: 3 mL) aspirate; 1 cm trephine biopsy

Processed Volume:

Same as Draw Volume

Collection:

If aspiration is impossible, a trephine biopsy should be obtained. Collect 5 mL of Na heparinized peripheral blood in addition to the bone marrow in all cases of newly diagnosed Acute Leukemia and Chronic Lymphocytic Leukemia.

Special Processing:

Store at room temperature. Do Not refrigerate of freeze. Ship at room temperature. Must arrive within 24 hours.

Patient Preparation:

Physician preference

Sample Rejection:

Clotted bone marrow

Interpretive

Reference Range:

46, XX or 46, XY

Methodology:

Determined by laboratory director based on clinical information.

References:

Fairview-University Diagnostic Laboratory Web Page http://labguide.fairview.org/diagnostic.asp

Abbott-Northwestern Cytogenetics Laboratory



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