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Lab Dept:
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Anatomic Pathology
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Test Name:
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CHROMOSOMES, BLOOD (ANW)
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General Information
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Lab Order Codes:
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CANW
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Synonyms:
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Chromosome Analysis, Blood; Karyotype
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CPT Codes:
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88230 – Tissue culture for non-neoplastic disorders; lymphocyte
88262 - Chromosome analysis; analyze 15 - 20 cells
88285 – Additional cells counted, each study (if appropriate)
88283 – Additonal specialized banding technique (if appropriate)
88280 – Additional karyotype (if appropriate)
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Test Includes:
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72 hour PHA stimulated culture with chromosome analysis with additional studies as indicated by findings.
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Logistics
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Test Indications:
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A standard chromosome study is performed on specimens suspected of having gross chromosome changes such as trisomy of chromosome 21 or mosaicism.
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Lab Testing Sections:
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Anatomic Pathology – Sendouts
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Referred to:
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Abbott Northwestern Laboratory – Cytogenetics (Test code: C40)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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7 - 14 days, testing performed daily (Stat: 3 – 7 days)
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Special Instructions:
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Request form must include date and time of specimen collection, attending physician, diagnosis (or reason for referral), clinical status, information regarding medication or transfusions, and specimen type.
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Specimen
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Specimen Type:
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Whole blood
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Container:
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Green top (Na heparin) tube
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Draw Volume:
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Children: 3 – 5 mL blood
Infants: 1 – 2 mL blood
Adults: 5 – 10 mL blood
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Processed Volume:
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Same as Draw Volume
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Use ANW request form B. Call (612-863-454, Cytogenetics MOB-402) prior to sending specimen or to request a pick-up.
Include physician’s name and phone number.
Inform if specimen is to run stat. If the specimen is stat and on a newborn, the specimen needs to be delivered ASAP and will be set up immediately. (Note: No one staffs ANW cyotgenetics from 7pm – 11pm but specimens should be delivered any way and the specimen will be set up when the night staff arrives.)
Diagnosis and genetic indications are required for testing.
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Patient Preparation:
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None
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Sample Rejection:
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Frozen or refrigerated specimen, mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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Interpretive report
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Methodology:
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Determined by Laboratory Director based on clinical information.
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References:
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Abbott Northwestern Cytogenetics Lab (April 2010)
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Updates:
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3/21/2007: ANW order code previously listed at 435.
4/14/2010: ANW order code previously listed as CSBLD
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