Clinics and Departments

Laboratory Services

Lab Dept:

Anatomic Pathology

Test Name:


General Information

Lab Order Codes:



Chromosome Analysis, Blood; Karyotype

CPT Codes:

88230 – Tissue culture for non-neoplastic disorders; lymphocyte
88262 - Chromosome analysis; analyze 15 - 20 cells
88285 – Additional cells counted, each study (if appropriate)
88283 – Additonal specialized banding technique (if appropriate)
88280 – Additional karyotype (if appropriate)

Test Includes:

72 hour PHA stimulated culture with chromosome analysis with additional studies as indicated by findings.


Test Indications:

A standard chromosome study is performed on specimens suspected of having gross chromosome changes such as trisomy of chromosome 21 or mosaicism.

Lab Testing Sections:

Anatomic Pathology – Sendouts

Referred to:

Abbott Northwestern Laboratory – Cytogenetics (Test code: C40)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

7 - 14 days, testing performed daily (Stat: 3 – 7 days)

Special Instructions:

Request form must include date and time of specimen collection, attending physician, diagnosis (or reason for referral), clinical status, information regarding medication or transfusions, and specimen type.


Specimen Type:

Whole blood


Green top (Na heparin) tube

Draw Volume:

Children: 3 – 5 mL blood
Infants: 1 – 2 mL blood
Adults: 5 – 10 mL blood

Processed Volume:

Same as Draw Volume


Routine venipuncture

Special Processing:

Lab Staff: Use ANW request form B. Call (612-863-454, Cytogenetics MOB-402) prior to sending specimen or to request a pick-up.

Include physician’s name and phone number.

Inform if specimen is to run stat. If the specimen is stat and on a newborn, the specimen needs to be delivered ASAP and will be set up immediately. (Note: No one staffs ANW cyotgenetics from 7pm – 11pm but specimens should be delivered any way and the specimen will be set up when the night staff arrives.)

Diagnosis and genetic indications are required for testing.

Patient Preparation:


Sample Rejection:

Frozen or refrigerated specimen; mislabeled or unlabeled specimens


Reference Range:

Interpretive report


Determined by Laboratory Director based on clinical information.


Abbott Northwestern Cytogenetics Lab (April 2010)


3/21/2007: ANW order code previously listed at 435.
4/14/2010: ANW order code previously listed as CSBLD

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